Cross-Cancer Pleiotropic Analysis Reveals Novel Susceptibility Loci for Lung Cancer

Cross-Cancer Pleiotropic Analysis Reveals Novel Susceptibility Loci for Lung Cancer

Genome-wide association studies (GWASs) have identified hundreds of single nucleotide polymorphisms (SNPs) associated with cancer risk, several of which have shown pleiotropic effects across cancers. Therefore, we performed a systematic cross-cancer pleiotropic analysis to detect the effects of GWAS...

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Bibliographic Details
Main Authors: Lijuan Wang, Meng Zhu, Yuzhuo Wang, Jingyi Fan, Qi Sun, Mengmeng Ji, Xikang Fan, Junxing Xie, Juncheng Dai, Guangfu Jin, Zhibin Hu, Hongxia Ma, Hongbing Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
lung cancer
genome-wide association studies
pleiotropy
susceptibility loci
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01492/full

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