Different Faces of Sinonasal Mass Lesions

Introduction Mass in the nasal cavity presents with a wide range of symptoms, when a presumptive diagnosis is often made with the help of imaging and endoscopy. This study focussed on correlating clinical diagnosis with the histopathological diagnosis so that appropriate treatment can be offered...

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Main Authors: Devika T, Shubha P Bhat, Vadisha Srinivas Bhat, Rajeshwary Aroor, Satheesh Kumar Bhandary B, Gautham MK, Samatha KJ
Format: Article
Language:English
Published: The Association of Otolaryngologists of India, West Bengal 2021-02-01
Series:Bengal Journal of Otolaryngology and Head Neck Surgery
Subjects:
Online Access:https://bjohns.in/journal3/index.php/bjohns/article/view/288
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author Devika T
Shubha P Bhat
Vadisha Srinivas Bhat
Rajeshwary Aroor
Satheesh Kumar Bhandary B
Gautham MK
Samatha KJ
author_facet Devika T
Shubha P Bhat
Vadisha Srinivas Bhat
Rajeshwary Aroor
Satheesh Kumar Bhandary B
Gautham MK
Samatha KJ
author_sort Devika T
collection DOAJ
description Introduction Mass in the nasal cavity presents with a wide range of symptoms, when a presumptive diagnosis is often made with the help of imaging and endoscopy. This study focussed on correlating clinical diagnosis with the histopathological diagnosis so that appropriate treatment can be offered to improve the quality of life of the patient. Materials and Methods The study included 120 cases who presented with symptoms and signs of mass in the nasal cavity, undergoing surgery or diagnostic biopsy. They were evaluated with a detailed history and clinical examination, diagnostic nasal endoscopy, and relevant radiological investigations. Histopathological examination of the biopsy of the excised specimen was performed by Haematoxylin and Eosin stain. Special stains and Immunohistochemistry (IHC) were performed whenever indicated. The clinical diagnosis was correlated with histopathological diagnosis. Results Nasal obstruction was the most frequent symptom followed by nasal discharge. Non-neoplastic lesions made up 85% of cases, while16% of cases were proved as neoplastic lesions. Among neoplastic lesions, 7% were benign, and 9% were malignant.  The inflammatory polyp was the most common non-neoplastic lesion. Fischer's exact test showed a correlation between clinical diagnosis and histopathological diagnosis. Non-neoplastic lesions were common in the 4th decade of life; benign lesions were common in the 3rd decade of life, while malignant lesions were common in the 5th decade of life. Conclusion Sinonasal masses present with overlapping clinical features, and sometimes the definite diagnosis is possible only by histopathological examination of the specimen. However, in the presence of characteristic clinical features, accurate clinical diagnosis is possible in most cases, and appropriate treatment can be performed without delay, pending histopathological examination.
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spelling doaj.art-09bed47c93cd43958ef168b0be39882a2024-03-02T14:39:34ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-24072021-02-0128310.47210/bjohns.2020.v28i3.288Different Faces of Sinonasal Mass LesionsDevika T0Shubha P Bhat1Vadisha Srinivas Bhat2Rajeshwary Aroor3Satheesh Kumar Bhandary B4Gautham MK5Samatha KJ6Department of ENT K S Hegde medical academy MangaloreDepartment of pathology K S Hegde Medical Academy Mangalorek S Hegde Medical Academy, Deralakatte, Mangalore, KarnatakaDepartment of ENT K S Hegde Medical Academy MangaloreDepartment of ENT K S Hegde Medical Academy MangaloreDepartment of ENT K S Hegde Medical Academy MangaloreDepartment of ENT K S Hegde Medical Academy MangaloreIntroduction Mass in the nasal cavity presents with a wide range of symptoms, when a presumptive diagnosis is often made with the help of imaging and endoscopy. This study focussed on correlating clinical diagnosis with the histopathological diagnosis so that appropriate treatment can be offered to improve the quality of life of the patient. Materials and Methods The study included 120 cases who presented with symptoms and signs of mass in the nasal cavity, undergoing surgery or diagnostic biopsy. They were evaluated with a detailed history and clinical examination, diagnostic nasal endoscopy, and relevant radiological investigations. Histopathological examination of the biopsy of the excised specimen was performed by Haematoxylin and Eosin stain. Special stains and Immunohistochemistry (IHC) were performed whenever indicated. The clinical diagnosis was correlated with histopathological diagnosis. Results Nasal obstruction was the most frequent symptom followed by nasal discharge. Non-neoplastic lesions made up 85% of cases, while16% of cases were proved as neoplastic lesions. Among neoplastic lesions, 7% were benign, and 9% were malignant.  The inflammatory polyp was the most common non-neoplastic lesion. Fischer's exact test showed a correlation between clinical diagnosis and histopathological diagnosis. Non-neoplastic lesions were common in the 4th decade of life; benign lesions were common in the 3rd decade of life, while malignant lesions were common in the 5th decade of life. Conclusion Sinonasal masses present with overlapping clinical features, and sometimes the definite diagnosis is possible only by histopathological examination of the specimen. However, in the presence of characteristic clinical features, accurate clinical diagnosis is possible in most cases, and appropriate treatment can be performed without delay, pending histopathological examination.https://bjohns.in/journal3/index.php/bjohns/article/view/288Mass, SinonasalPresentationHistopathology
spellingShingle Devika T
Shubha P Bhat
Vadisha Srinivas Bhat
Rajeshwary Aroor
Satheesh Kumar Bhandary B
Gautham MK
Samatha KJ
Different Faces of Sinonasal Mass Lesions
Bengal Journal of Otolaryngology and Head Neck Surgery
Mass, Sinonasal
Presentation
Histopathology
title Different Faces of Sinonasal Mass Lesions
title_full Different Faces of Sinonasal Mass Lesions
title_fullStr Different Faces of Sinonasal Mass Lesions
title_full_unstemmed Different Faces of Sinonasal Mass Lesions
title_short Different Faces of Sinonasal Mass Lesions
title_sort different faces of sinonasal mass lesions
topic Mass, Sinonasal
Presentation
Histopathology
url https://bjohns.in/journal3/index.php/bjohns/article/view/288
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AT satheeshkumarbhandaryb differentfacesofsinonasalmasslesions
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