PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH
ABSTRACT Background: Studies related to obesity have shown association with metabolic syndrome. Data showing that obesity is capable to cause low grade chronic inflammation, without its classic signs and symptoms, call attention to researches to study different cells types and the mechanism of the...
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| Format: | Article |
| Language: | English |
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Colégio Brasileiro de Cirurgia Digestiva
2016-12-01
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| Series: | ABCD: Arquivos Brasileiros de Cirurgia Digestiva |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202016000400252&tlng=pt |
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| author | Luciano Dias de Oliveira REIS Paulo Afonso Nunes NASSIF Fernando Issamu TABUSHI Fábio Quirillo MILLÉO Giovani Marino FAVERO Bruno Luiz ARIEDE Cassiana Franco Dias Dos REIS Bruno Franco DALABONA |
| author_facet | Luciano Dias de Oliveira REIS Paulo Afonso Nunes NASSIF Fernando Issamu TABUSHI Fábio Quirillo MILLÉO Giovani Marino FAVERO Bruno Luiz ARIEDE Cassiana Franco Dias Dos REIS Bruno Franco DALABONA |
| author_sort | Luciano Dias de Oliveira REIS |
| collection | DOAJ |
| description | ABSTRACT Background: Studies related to obesity have shown association with metabolic syndrome. Data showing that obesity is capable to cause low grade chronic inflammation, without its classic signs and symptoms, call attention to researches to study different cells types and the mechanism of the inflammatory process. Aim: To evaluate the variation of glycated hemoglobin (HbA1c) and the pro-inflammatory cytokine interleukin-6 (IL6) in diabetic patients with BMI <35 kg/m2 in the pre and postoperative of partial duodenal switch. Method: Nine patients were studied before and one year after the operation and the variation of the serum IL6 was measured by Elisa. The changes of HbA1c were also registered. Results: The pre-operative IL6 levels reached 65,50436±2,911993 pg/ml and one year after de operation 39,47739±3,410057 and the HbA1c average of 10,67 and 5.8 in the same period. Conclusion: The partial duodenal switch was efficient to control one year after the procedure the chronic inflammatory process caused by the diabetes mellitus type 2 with BMI <35 by dropping the IL6 levels and bringing the HbA1c to normal. |
| first_indexed | 2024-12-18T02:30:09Z |
| format | Article |
| id | doaj.art-09bf8f2f4db94dde9648401b71e39510 |
| institution | Directory Open Access Journal |
| issn | 0102-6720 |
| language | English |
| last_indexed | 2024-12-18T02:30:09Z |
| publishDate | 2016-12-01 |
| publisher | Colégio Brasileiro de Cirurgia Digestiva |
| record_format | Article |
| series | ABCD: Arquivos Brasileiros de Cirurgia Digestiva |
| spelling | doaj.art-09bf8f2f4db94dde9648401b71e395102022-12-21T21:23:55ZengColégio Brasileiro de Cirurgia DigestivaABCD: Arquivos Brasileiros de Cirurgia Digestiva0102-67202016-12-0129425225610.1590/0102-6720201600040009PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCHLuciano Dias de Oliveira REISPaulo Afonso Nunes NASSIFFernando Issamu TABUSHIFábio Quirillo MILLÉOGiovani Marino FAVEROBruno Luiz ARIEDECassiana Franco Dias Dos REISBruno Franco DALABONAABSTRACT Background: Studies related to obesity have shown association with metabolic syndrome. Data showing that obesity is capable to cause low grade chronic inflammation, without its classic signs and symptoms, call attention to researches to study different cells types and the mechanism of the inflammatory process. Aim: To evaluate the variation of glycated hemoglobin (HbA1c) and the pro-inflammatory cytokine interleukin-6 (IL6) in diabetic patients with BMI <35 kg/m2 in the pre and postoperative of partial duodenal switch. Method: Nine patients were studied before and one year after the operation and the variation of the serum IL6 was measured by Elisa. The changes of HbA1c were also registered. Results: The pre-operative IL6 levels reached 65,50436±2,911993 pg/ml and one year after de operation 39,47739±3,410057 and the HbA1c average of 10,67 and 5.8 in the same period. Conclusion: The partial duodenal switch was efficient to control one year after the procedure the chronic inflammatory process caused by the diabetes mellitus type 2 with BMI <35 by dropping the IL6 levels and bringing the HbA1c to normal.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202016000400252&tlng=ptMetabolic syndromeObesityDiabetes mellitus type 2Bariatric surgeryInterleukin-6. |
| spellingShingle | Luciano Dias de Oliveira REIS Paulo Afonso Nunes NASSIF Fernando Issamu TABUSHI Fábio Quirillo MILLÉO Giovani Marino FAVERO Bruno Luiz ARIEDE Cassiana Franco Dias Dos REIS Bruno Franco DALABONA PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH ABCD: Arquivos Brasileiros de Cirurgia Digestiva Metabolic syndrome Obesity Diabetes mellitus type 2 Bariatric surgery Interleukin-6. |
| title | PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH |
| title_full | PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH |
| title_fullStr | PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH |
| title_full_unstemmed | PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH |
| title_short | PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH |
| title_sort | preliminary analysis of interleukin 6 changes in pre and postoperative in diabetic patients with bmi 35 submitted to partial duodenal switch |
| topic | Metabolic syndrome Obesity Diabetes mellitus type 2 Bariatric surgery Interleukin-6. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202016000400252&tlng=pt |
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