Dietary sulforaphane inhibits histone deacetylase activity in B16 melanoma cells

Dietary sulforaphane inhibits histone deacetylase activity in B16 melanoma cells

Dietary sulforaphane (SF) exerts anticancer effects via epigenetic changes resulting from the inhibition of histone deacetylase (HDAC) activity in colon and prostate cancer cells. The present study aimed to evaluate the inhibition of HDAC activity by SF and its effect on apoptosis in B16 melanoma ce...

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Bibliographic Details
Main Authors: Wu Yuanfeng, Xiao Gongnian, Mao Jianwei, Liu Shiwang, Huang Jun, Mei Lehe
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Functional Foods
Subjects:
Sulforaphane
Histone deacetylase
Melanoma
Apoptosis
Cell cycle arrest
Functional food
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615003606

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