Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?”
Abstract Background: The neutrophil-lymphocyte ratio (NLR) and monocyte-lymphocyte ratio(MLR) are useful biomarkers of inflammation used in many diseases to evaluate bacteremia, disease activity, recurrence rate, surveillance and prognosis. Objective: Aim of this study was to evaluate NLR and MLR...
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| Format: | Article |
| Language: | English |
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Rabia Yılmaz
2021-07-01
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| Series: | Journal of Contemporary Medicine |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1389425 |
| _version_ | 1797860594552930304 |
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| author | Şefika Elmas Bozdemir |
| author_facet | Şefika Elmas Bozdemir |
| author_sort | Şefika Elmas Bozdemir |
| collection | DOAJ |
| description | Abstract
Background: The neutrophil-lymphocyte ratio (NLR) and monocyte-lymphocyte ratio(MLR) are useful biomarkers of inflammation used in many diseases to evaluate bacteremia, disease activity, recurrence rate, surveillance and prognosis.
Objective: Aim of this study was to evaluate NLR and MLR in the differential diagnosis of children with pulmonary tuberculosis disease from CAP.
Materials and Methods: I reviewed hospital-records of 50 children with pulmonary tuberculosis disease in the Pediatric Infectious Disease Ward between June 2016 and December 2018, and compared; NLR and MLR with 50 CAP and 50 healthy children. Also; erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) were compared between the tuberculosis and CAP group.
Results: When 3 groups were compared there was significant difference among NLR and MLR values between 3 groups. In pairwise-comparisons, there was significant difference among NLR and MLR values between tuberculosis versus healthy controls, and CAP versus healthy controls. However, there was no significant difference among NLR, MLR values between tuberculosis versus CAP groups.
Conclusion: This study is unique that evluates NLR and MLR in tuberculosis differentiation. Although NLR and MLR values are useful biomarkers of inflammation in both pulmonary tuberculosis and CAP seperately, they’re not as useful as expected in differentiating tuberculosis from CAP in children. |
| first_indexed | 2024-04-09T21:49:29Z |
| format | Article |
| id | doaj.art-09ca14eed12d442a8f800ef2601564e2 |
| institution | Directory Open Access Journal |
| issn | 2667-7180 |
| language | English |
| last_indexed | 2024-04-09T21:49:29Z |
| publishDate | 2021-07-01 |
| publisher | Rabia Yılmaz |
| record_format | Article |
| series | Journal of Contemporary Medicine |
| spelling | doaj.art-09ca14eed12d442a8f800ef2601564e22023-03-24T19:43:25ZengRabia YılmazJournal of Contemporary Medicine2667-71802021-07-0111450050510.16899/jcm.8238441809Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?”Şefika Elmas Bozdemir0sağlık bakanlığı dörtçelik çocuk hastanesiAbstract Background: The neutrophil-lymphocyte ratio (NLR) and monocyte-lymphocyte ratio(MLR) are useful biomarkers of inflammation used in many diseases to evaluate bacteremia, disease activity, recurrence rate, surveillance and prognosis. Objective: Aim of this study was to evaluate NLR and MLR in the differential diagnosis of children with pulmonary tuberculosis disease from CAP. Materials and Methods: I reviewed hospital-records of 50 children with pulmonary tuberculosis disease in the Pediatric Infectious Disease Ward between June 2016 and December 2018, and compared; NLR and MLR with 50 CAP and 50 healthy children. Also; erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) were compared between the tuberculosis and CAP group. Results: When 3 groups were compared there was significant difference among NLR and MLR values between 3 groups. In pairwise-comparisons, there was significant difference among NLR and MLR values between tuberculosis versus healthy controls, and CAP versus healthy controls. However, there was no significant difference among NLR, MLR values between tuberculosis versus CAP groups. Conclusion: This study is unique that evluates NLR and MLR in tuberculosis differentiation. Although NLR and MLR values are useful biomarkers of inflammation in both pulmonary tuberculosis and CAP seperately, they’re not as useful as expected in differentiating tuberculosis from CAP in children.https://dergipark.org.tr/tr/download/article-file/1389425tuberculosiscommunity acquired pneumoniachildneutrophil to lymphocyte ratiomonocyte to lymphocyte ratiotüberküloztoplum kaynaklı pnömoniçocuknotrofil lenfosit oranımonosit lenfosit oranı |
| spellingShingle | Şefika Elmas Bozdemir Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?” Journal of Contemporary Medicine tuberculosis community acquired pneumonia child neutrophil to lymphocyte ratio monocyte to lymphocyte ratio tüberküloz toplum kaynaklı pnömoni çocuk notrofil lenfosit oranı monosit lenfosit oranı |
| title | Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?” |
| title_full | Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?” |
| title_fullStr | Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?” |
| title_full_unstemmed | Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?” |
| title_short | Seeking New Parameters In Differentiating Child Tuberculosis From Community Acquired Pneumonia- Is It Possible?” |
| title_sort | seeking new parameters in differentiating child tuberculosis from community acquired pneumonia is it possible |
| topic | tuberculosis community acquired pneumonia child neutrophil to lymphocyte ratio monocyte to lymphocyte ratio tüberküloz toplum kaynaklı pnömoni çocuk notrofil lenfosit oranı monosit lenfosit oranı |
| url | https://dergipark.org.tr/tr/download/article-file/1389425 |
| work_keys_str_mv | AT sefikaelmasbozdemir seekingnewparametersindifferentiatingchildtuberculosisfromcommunityacquiredpneumoniaisitpossible |