Olfactory disorder in Parkinson's disease
Olfactory dysfunction is the most common early non-motor symptom of Parkinson's disease (PD), which is used as a marker for the diagnosis of PD. The mechanism of olfactory dysfunction is very complex, which is a challenge in the research. The neuromediator such as the accumulation of α-synuclei...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2023-06-01
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| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-6-994.pdf |
| _version_ | 1827390955310809088 |
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| author | REN Peng, CHEN Yali, ZHANG Xianwen |
| author_facet | REN Peng, CHEN Yali, ZHANG Xianwen |
| author_sort | REN Peng, CHEN Yali, ZHANG Xianwen |
| collection | DOAJ |
| description | Olfactory dysfunction is the most common early non-motor symptom of Parkinson's disease (PD), which is used as a marker for the diagnosis of PD. The mechanism of olfactory dysfunction is very complex, which is a challenge in the research. The neuromediator such as the accumulation of α-synuclein, dopamine (DA), acetylcholine (ACh), 5-hydroxytryptamine (5-HT) and inflammatory factors are implicated in the olfactory dysfunction in PD. To further study the mechanism of olfactory dysfunction in PD may provide new ideas and therapeutic targets for treatment. |
| first_indexed | 2024-03-08T17:02:36Z |
| format | Article |
| id | doaj.art-09cb9b8a42b84367aeb53272f0e695d3 |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T17:02:36Z |
| publishDate | 2023-06-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-09cb9b8a42b84367aeb53272f0e695d32024-01-04T07:33:02ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252023-06-0143699499710.16352/j.issn.1001-6325.2023.06.0994Olfactory disorder in Parkinson's diseaseREN Peng, CHEN Yali, ZHANG Xianwen0Medical College, Kunming University of Science and Technology, Kunming 650500, ChinaOlfactory dysfunction is the most common early non-motor symptom of Parkinson's disease (PD), which is used as a marker for the diagnosis of PD. The mechanism of olfactory dysfunction is very complex, which is a challenge in the research. The neuromediator such as the accumulation of α-synuclein, dopamine (DA), acetylcholine (ACh), 5-hydroxytryptamine (5-HT) and inflammatory factors are implicated in the olfactory dysfunction in PD. To further study the mechanism of olfactory dysfunction in PD may provide new ideas and therapeutic targets for treatment.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-6-994.pdfparkinson's disease|olfactory dysfunction|α-synuclein|inflammation response|neuromediator |
| spellingShingle | REN Peng, CHEN Yali, ZHANG Xianwen Olfactory disorder in Parkinson's disease Jichu yixue yu linchuang parkinson's disease|olfactory dysfunction|α-synuclein|inflammation response|neuromediator |
| title | Olfactory disorder in Parkinson's disease |
| title_full | Olfactory disorder in Parkinson's disease |
| title_fullStr | Olfactory disorder in Parkinson's disease |
| title_full_unstemmed | Olfactory disorder in Parkinson's disease |
| title_short | Olfactory disorder in Parkinson's disease |
| title_sort | olfactory disorder in parkinson s disease |
| topic | parkinson's disease|olfactory dysfunction|α-synuclein|inflammation response|neuromediator |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-6-994.pdf |
| work_keys_str_mv | AT renpengchenyalizhangxianwen olfactorydisorderinparkinsonsdisease |