OSR1 and SPAK Sensitivity of Large-Conductance Ca2+ Activated K+ Channel

OSR1 and SPAK Sensitivity of Large-Conductance Ca2+ Activated K+ Channel

Background/Aims: The oxidative stress-responsive kinase 1 (OSR1) and the serine/threonine kinases SPAK (SPS1-related proline/alanine-rich kinase) are under the control of WNK (with-no-K [Lys]) kinases. OSR1 and SPAK participate in diverse functions including cell volume regulation and neuronal excit...

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Bibliographic Details
Main Authors: Bernat Elvira, Yogesh Singh, Jamshed Warsi, Carlos Munoz, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Neuronal excitation
BK channels
Oxidative stress-responsive kinase 1
SPS1-related proline/alanine-rich kinase
WNK
Online Access:http://www.karger.com/Article/FullText/443105

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