Giant Aggressive Extraocular Sebaceous Carcinoma: A Case Report

Fang Liu, Fei Qi, Xiuying Zhang, Mei Cao Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Fang LiuDepartment of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaT...

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Main Authors: Liu F, Qi F, Zhang X, Cao M
Format: Article
Language:English
Published: Dove Medical Press 2021-09-01
Series:Clinical, Cosmetic and Investigational Dermatology
Subjects:
Online Access:https://www.dovepress.com/giant-aggressive-extraocular-sebaceous-carcinoma-a-case-report-peer-reviewed-fulltext-article-CCID
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author Liu F
Qi F
Zhang X
Cao M
author_facet Liu F
Qi F
Zhang X
Cao M
author_sort Liu F
collection DOAJ
description Fang Liu, Fei Qi, Xiuying Zhang, Mei Cao Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Fang LiuDepartment of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaTel +86-10-85231688Fax +86-10-85231217Email roseliufang@qq.comAbstract: Sebaceous carcinoma (SC) is a rare, aggressive malignancy. Most lesions occur in the periocular region, with few cases presenting with extraocular lesions. Here, we report a case of an 89-year-old woman with a 3-month history of a rapidly growing giant extraocular SC. The diagnosis was based on skin biopsy findings. We advised the patient to undergo surgical excision of the carcinoma. However, the patient and her family rejected our proposed surgical treatment, opting for topical traditional Chinese medicine as alternative treatment. The patient subsequently died of unknown causes at home, four months after the first visit. This case of treatment failure emphasizes the importance of early detection and treatment for these aggressive tumors.Keywords: sebaceous carcinoma, extraocular, skin neoplasms, malignancy, Muir-Torre syndrome
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spelling doaj.art-09d10f84b8cb47008bc9f0992c21d3d92022-12-21T22:07:14ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152021-09-01Volume 141351135469193Giant Aggressive Extraocular Sebaceous Carcinoma: A Case ReportLiu FQi FZhang XCao MFang Liu, Fei Qi, Xiuying Zhang, Mei Cao Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Fang LiuDepartment of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaTel +86-10-85231688Fax +86-10-85231217Email roseliufang@qq.comAbstract: Sebaceous carcinoma (SC) is a rare, aggressive malignancy. Most lesions occur in the periocular region, with few cases presenting with extraocular lesions. Here, we report a case of an 89-year-old woman with a 3-month history of a rapidly growing giant extraocular SC. The diagnosis was based on skin biopsy findings. We advised the patient to undergo surgical excision of the carcinoma. However, the patient and her family rejected our proposed surgical treatment, opting for topical traditional Chinese medicine as alternative treatment. The patient subsequently died of unknown causes at home, four months after the first visit. This case of treatment failure emphasizes the importance of early detection and treatment for these aggressive tumors.Keywords: sebaceous carcinoma, extraocular, skin neoplasms, malignancy, Muir-Torre syndromehttps://www.dovepress.com/giant-aggressive-extraocular-sebaceous-carcinoma-a-case-report-peer-reviewed-fulltext-article-CCIDsebaceous carcinomaextraocularskin neoplasmsmalignancymuir-torre syndrome
spellingShingle Liu F
Qi F
Zhang X
Cao M
Giant Aggressive Extraocular Sebaceous Carcinoma: A Case Report
Clinical, Cosmetic and Investigational Dermatology
sebaceous carcinoma
extraocular
skin neoplasms
malignancy
muir-torre syndrome
title Giant Aggressive Extraocular Sebaceous Carcinoma: A Case Report
title_full Giant Aggressive Extraocular Sebaceous Carcinoma: A Case Report
title_fullStr Giant Aggressive Extraocular Sebaceous Carcinoma: A Case Report
title_full_unstemmed Giant Aggressive Extraocular Sebaceous Carcinoma: A Case Report
title_short Giant Aggressive Extraocular Sebaceous Carcinoma: A Case Report
title_sort giant aggressive extraocular sebaceous carcinoma a case report
topic sebaceous carcinoma
extraocular
skin neoplasms
malignancy
muir-torre syndrome
url https://www.dovepress.com/giant-aggressive-extraocular-sebaceous-carcinoma-a-case-report-peer-reviewed-fulltext-article-CCID
work_keys_str_mv AT liuf giantaggressiveextraocularsebaceouscarcinomaacasereport
AT qif giantaggressiveextraocularsebaceouscarcinomaacasereport
AT zhangx giantaggressiveextraocularsebaceouscarcinomaacasereport
AT caom giantaggressiveextraocularsebaceouscarcinomaacasereport