Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?

Cognitive impairment (CI) associated with brain aging is a consequence of disorders varying in etiology and pathogenesis, which often coexist in elderly patients and can have a mutual impact on the clinical manifestation, severity, and rate of progression of CI. Alzheimer's disease (AD) and vas...

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Main Authors: G. R. Tabeeva, E. A. Kirjanova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2019-11-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/1184
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author G. R. Tabeeva
E. A. Kirjanova
author_facet G. R. Tabeeva
E. A. Kirjanova
author_sort G. R. Tabeeva
collection DOAJ
description Cognitive impairment (CI) associated with brain aging is a consequence of disorders varying in etiology and pathogenesis, which often coexist in elderly patients and can have a mutual impact on the clinical manifestation, severity, and rate of progression of CI. Alzheimer's disease (AD) and vascular CI are the most common forms of dementia in the elderly. In recent decades, there has been increasing evidence that there is a close relationship between these forms due to a substantial overlap of their risk factors, clinical manifestations, neuromorphological changes, as well as genetic and neuroimaging biomarkers. The complex multicomponent relationship of these disorders also makes it difficult to elaborate effective preventive and therapeutic approaches in these patients.
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spelling doaj.art-09d2c7db90f245faaf416b3254307a7a2023-03-13T08:42:18ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422019-11-0111311011510.14412/2074-2711-2019-3-110-115901Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?G. R. Tabeeva0E. A. Kirjanova1I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaCognitive impairment (CI) associated with brain aging is a consequence of disorders varying in etiology and pathogenesis, which often coexist in elderly patients and can have a mutual impact on the clinical manifestation, severity, and rate of progression of CI. Alzheimer's disease (AD) and vascular CI are the most common forms of dementia in the elderly. In recent decades, there has been increasing evidence that there is a close relationship between these forms due to a substantial overlap of their risk factors, clinical manifestations, neuromorphological changes, as well as genetic and neuroimaging biomarkers. The complex multicomponent relationship of these disorders also makes it difficult to elaborate effective preventive and therapeutic approaches in these patients.https://nnp.ima-press.net/nnp/article/view/1184chronic cerebrovascular diseasealzheimer's diseasevascular cognitive impairmentvascular dementia
spellingShingle G. R. Tabeeva
E. A. Kirjanova
Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?
Неврология, нейропсихиатрия, психосоматика
chronic cerebrovascular disease
alzheimer's disease
vascular cognitive impairment
vascular dementia
title Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?
title_full Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?
title_fullStr Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?
title_full_unstemmed Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?
title_short Vascular cognitive impairment and Alzheimer's disease: Is there a relationship between them?
title_sort vascular cognitive impairment and alzheimer s disease is there a relationship between them
topic chronic cerebrovascular disease
alzheimer's disease
vascular cognitive impairment
vascular dementia
url https://nnp.ima-press.net/nnp/article/view/1184
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AT eakirjanova vascularcognitiveimpairmentandalzheimersdiseaseistherearelationshipbetweenthem