Hydroxy-Selenomethionine Mitigated Chronic Heat Stress-Induced Porcine Splenic Damage via Activation of Nrf2/Keap1 Signal and Suppression of NFκb and STAT Signal

Hydroxy-Selenomethionine Mitigated Chronic Heat Stress-Induced Porcine Splenic Damage via Activation of Nrf2/Keap1 Signal and Suppression of NFκb and STAT Signal

Chronic heat stress (CHS) compromised the immunity and spleen immunological function of pigs, which may associate with antioxidant suppression and splenocyte apoptosis and splenic inflammation. Selenium (Se) exhibited antioxidant function and immunomodulatory through selenoprotein. Thus, this study...

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Bibliographic Details
Main Authors: Yan Liu, Shenggang Yin, Ying He, Jiayong Tang, Junning Pu, Gang Jia, Guangmang Liu, Gang Tian, Xiaoling Chen, Jingyi Cai, Bo Kang, Lianqiang Che, Hua Zhao
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
chronic heat stress
spleen
antioxidant
inflammation
hydroxy-selenomethionine
pigs
Online Access:https://www.mdpi.com/1422-0067/24/7/6461

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