Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion

A 36-year-old male patient is referred for urology review for haematuria following cyclophosphamide and mesna administration for allogeneic stem cell transplant for treatment of acute lymphoblastic leukaemia. Severe haematuria continued despite multiple interventions including continuous bladder irr...

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Main Authors: Gerald Mak, Wenjie Zhong, Vincent Chan, Scott Leslie
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442021002217
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author Gerald Mak
Wenjie Zhong
Vincent Chan
Scott Leslie
author_facet Gerald Mak
Wenjie Zhong
Vincent Chan
Scott Leslie
author_sort Gerald Mak
collection DOAJ
description A 36-year-old male patient is referred for urology review for haematuria following cyclophosphamide and mesna administration for allogeneic stem cell transplant for treatment of acute lymphoblastic leukaemia. Severe haematuria continued despite multiple interventions including continuous bladder irrigation and cystoscopic fulguration, with formation of consolidated clot in the bladder. A successful cystotomy for removal of clot and initiation of alum was performed, leading to resolution of haematuria.
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spelling doaj.art-09d3a654e16a4faba01e1d1c3d7cc8242022-12-21T21:47:16ZengElsevierUrology Case Reports2214-44202021-11-0139101781Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusionGerald Mak0Wenjie Zhong1Vincent Chan2Scott Leslie3Corresponding author. Department of Urology, Royal Prince Alfred Hospital, Missenden Rd, Camperdown, Sydney, NSW, 2050, Australia.; Department of Urology, Royal Prince Alfred Hospital, Sydney, AustraliaDepartment of Urology, Royal Prince Alfred Hospital, Sydney, AustraliaDepartment of Urology, Royal Prince Alfred Hospital, Sydney, AustraliaDepartment of Urology, Royal Prince Alfred Hospital, Sydney, AustraliaA 36-year-old male patient is referred for urology review for haematuria following cyclophosphamide and mesna administration for allogeneic stem cell transplant for treatment of acute lymphoblastic leukaemia. Severe haematuria continued despite multiple interventions including continuous bladder irrigation and cystoscopic fulguration, with formation of consolidated clot in the bladder. A successful cystotomy for removal of clot and initiation of alum was performed, leading to resolution of haematuria.http://www.sciencedirect.com/science/article/pii/S2214442021002217Hemorrhagic cystitisCystotomyCyclophosphamideAlum
spellingShingle Gerald Mak
Wenjie Zhong
Vincent Chan
Scott Leslie
Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion
Urology Case Reports
Hemorrhagic cystitis
Cystotomy
Cyclophosphamide
Alum
title Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion
title_full Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion
title_fullStr Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion
title_full_unstemmed Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion
title_short Successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and BK virus with cystotomy and alum infusion
title_sort successful management of severe refractory haemorrhagic cystitis secondary to cyclophosphamide and bk virus with cystotomy and alum infusion
topic Hemorrhagic cystitis
Cystotomy
Cyclophosphamide
Alum
url http://www.sciencedirect.com/science/article/pii/S2214442021002217
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AT vincentchan successfulmanagementofsevererefractoryhaemorrhagiccystitissecondarytocyclophosphamideandbkviruswithcystotomyandaluminfusion
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