Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers
By following morphological changes in supramolecular assemblies of silkworm silk, the authors find that while the initial steps of secretion and storage inside the silk gland follow the micelle theory of silk assembly, a phase rearrangement occurs inside microscale spherical structures that gives ri...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35505-w |
| _version_ | 1797977315396812800 |
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| author | D. Eliaz S. Paul D. Benyamin A. Cernescu S. R. Cohen I. Rosenhek-Goldian O. Brookstein M. E. Miali A. Solomonov M. Greenblatt Y. Levy U. Raviv A. Barth U. Shimanovich |
| author_facet | D. Eliaz S. Paul D. Benyamin A. Cernescu S. R. Cohen I. Rosenhek-Goldian O. Brookstein M. E. Miali A. Solomonov M. Greenblatt Y. Levy U. Raviv A. Barth U. Shimanovich |
| author_sort | D. Eliaz |
| collection | DOAJ |
| description | By following morphological changes in supramolecular assemblies of silkworm silk, the authors find that while the initial steps of secretion and storage inside the silk gland follow the micelle theory of silk assembly, a phase rearrangement occurs inside microscale spherical structures that gives rise to the formation of nanoscale spherical assemblies. |
| first_indexed | 2024-04-11T05:05:58Z |
| format | Article |
| id | doaj.art-09d6802c5537496abb26a108187f4c16 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T05:05:58Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-09d6802c5537496abb26a108187f4c162022-12-25T12:21:02ZengNature PortfolioNature Communications2041-17232022-12-0113111210.1038/s41467-022-35505-wMicro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibersD. Eliaz0S. Paul1D. Benyamin2A. Cernescu3S. R. Cohen4I. Rosenhek-Goldian5O. Brookstein6M. E. Miali7A. Solomonov8M. Greenblatt9Y. Levy10U. Raviv11A. Barth12U. Shimanovich13Department of Molecular Chemistry and Materials Science, Faculty of Chemistry, Weizmann Institute of ScienceDepartment of Biochemistry and Biophysics, Stockholm UniversityInstitute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat RamNeaspec—Attocube Systems AG, Eglfinger Weg 2Department of Chemical Research Support, Weizmann Institute of ScienceDepartment of Chemical Research Support, Weizmann Institute of ScienceDepartment of Molecular Chemistry and Materials Science, Faculty of Chemistry, Weizmann Institute of ScienceDepartment of Molecular Chemistry and Materials Science, Faculty of Chemistry, Weizmann Institute of ScienceDepartment of Molecular Chemistry and Materials Science, Faculty of Chemistry, Weizmann Institute of ScienceDepartment of Chemical and Structural Biology, Weizmann Institute of ScienceDepartment of Chemical and Structural Biology, Weizmann Institute of ScienceInstitute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat RamDepartment of Biochemistry and Biophysics, Stockholm UniversityDepartment of Molecular Chemistry and Materials Science, Faculty of Chemistry, Weizmann Institute of ScienceBy following morphological changes in supramolecular assemblies of silkworm silk, the authors find that while the initial steps of secretion and storage inside the silk gland follow the micelle theory of silk assembly, a phase rearrangement occurs inside microscale spherical structures that gives rise to the formation of nanoscale spherical assemblies.https://doi.org/10.1038/s41467-022-35505-w |
| spellingShingle | D. Eliaz S. Paul D. Benyamin A. Cernescu S. R. Cohen I. Rosenhek-Goldian O. Brookstein M. E. Miali A. Solomonov M. Greenblatt Y. Levy U. Raviv A. Barth U. Shimanovich Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers Nature Communications |
| title | Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers |
| title_full | Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers |
| title_fullStr | Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers |
| title_full_unstemmed | Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers |
| title_short | Micro and nano-scale compartments guide the structural transition of silk protein monomers into silk fibers |
| title_sort | micro and nano scale compartments guide the structural transition of silk protein monomers into silk fibers |
| url | https://doi.org/10.1038/s41467-022-35505-w |
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