Trabecular Meshwork Mitochondrial Function and Oxidative Stress

Trabecular Meshwork Mitochondrial Function and Oxidative Stress

Purpose: To identify racial differences of oxidative damage and stress and mitochondrial function in human trabecular meshwork (TM). Design: Experimental study. Participants: One hundred seventy-three eyes of 173 patients undergoing intraocular surgery provided aqueous humor (AH) for analysis. Trabe...

Full description

Bibliographic Details
Main Authors:	Hongli Wu, PhD, Ying-Bo Shui, MD, PhD, Ying Liu, BS, Xiaobin Liu, PhD, Carla J. Siegfried, MD
Format:	Article
Language:	English
Published:	Elsevier 2022-03-01
Series:	Ophthalmology Science
Subjects:	Glaucoma Mitochondrial function Oxidative damage Racial disparity Trabecular meshwork
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666914521001056

Similar Items

A20 Attenuates the Fibrotic Response in the Trabecular Meshwork
by: Philip Mzyk, et al.
Published: (2022-02-01)

Overexpression and Activation of αvβ3 Integrin Differentially Affects TGFβ2 Signaling in Human Trabecular Meshwork Cells
by: Mark S. Filla, et al.
Published: (2021-07-01)

Apoptosis in the iris and trabecular meshwork of medically treated and untreated primary open angle glaucoma patients
by: Zeynep Aktas, et al.
Published: (2013-12-01)

Exploiting biomaterial approaches to manufacture an artificial trabecular meshwork: A progress report
by: Devon J. Crouch, et al.
Published: (2021-03-01)

Dexamethasone Modulates the Dynamics of Wnt Signaling in Human Trabecular Meshwork Cells
by: Chi Zhang, et al.
Published: (2023-05-01)

Transcriptome analysis for the identification of cellular markers related to trabecular meshwork differentiation
by: Padmapriya Sathiyanathan, et al.
Published: (2017-05-01)

Toll-Like Receptor 4 Signaling in the Trabecular Meshwork
by: Philip Mzyk, et al.
Published: (2022-07-01)

Integrin Crosstalk and Its Effect on the Biological Functions of the Trabecular Meshwork/Schlemm’s Canal
by: Jennifer A. Faralli, et al.
Published: (2022-04-01)

Regeneration of trabecular meshwork in primary open angle glaucoma by stem cell therapy: a new treatment approach
by: Vingolo EM, et al.
Published: (2019-04-01)

Cell-Based Therapies for Trabecular Meshwork Regeneration to Treat Glaucoma
by: Shayshadri Mallick, et al.
Published: (2021-08-01)

Data on differentially expressed proteins in rock inhibitor-treated human trabecular meshwork cells using SWATH-based proteomics
by: Sze-Wan Shan, et al.
Published: (2020-08-01)

Autoantigens in the trabecular meshwork and glaucoma‐specific alterations in the natural autoantibody repertoire
by: Vanessa M Beutgen, et al.
Published: (2020-01-01)

Histopathologic correlates of trabecular meshwork in microincisional trabeculectomy
by: Aparna Rao
Published: (2024-01-01)

Cell senescence alters responses of porcine trabecular meshwork cells to shear stress
by: Ruotian Du, et al.
Published: (2022-11-01)

Protective Effects of Rapamycin on Trabecular Meshwork Cells in Glucocorticoid-Induced Glaucoma Mice
by: Xiaolu Zhu, et al.
Published: (2020-07-01)

An Optimized Method to Decellularize Human Trabecular Meshwork
by: Devon J. Crouch, et al.
Published: (2022-04-01)

Fibronectin extra domain A (FN-EDA) causes glaucomatous trabecular meshwork, retina, and optic nerve damage in mice
by: Timur A. Mavlyutov, et al.
Published: (2022-05-01)

The Effects of Mechanical Stretch on Integrins and Filopodial-Associated Proteins in Normal and Glaucomatous Trabecular Meshwork Cells
by: Yong-Feng Yang, et al.
Published: (2022-04-01)

Oxidative stress and antioxidants in the trabecular meshwork
by: Mingxuan Wang, et al.
Published: (2019-11-01)

Identification, quantification and age-related changes of human trabecular meshwork stem cells
by: Yogapriya Sundaresan, et al.
Published: (2019-10-01)

Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals
by: Lijuan Xu, et al.
Published: (2023-01-01)

Profile of cytokines in aqueous humor and trabecular meshwork cell culture in patients with pseudoexfoliation glaucoma
by: V. V. Rakhmanov, et al.
Published: (2021-03-01)

Research progress of trabecular meshwork cell oxidative stress in the pathogenesis of glaucoma
by: Jing-Yi Wu, et al.
Published: (2021-11-01)

Effect of IL-6 on fibronectin in bovine trabecular meshwork cells cultured <i>in vitro</i>
by: Pan Liu, et al.
Published: (2019-06-01)

Freeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model
by: Yalong Dang, et al.
Published: (2017-08-01)

Investigating the Relationship between Glaucoma Prevalence and Trabecular Meshwork Length
by: Wungrak Choi, et al.
Published: (2021-03-01)

Gene transfer to human trabecular meshwork cells in vitro and ex vivo using HIV-based lentivirus
by: Yan Xiang, et al.
Published: (2014-12-01)

Glucocorticoids Preferentially Influence Expression of Nucleoskeletal Actin Network and Cell Adhesive Proteins in Human Trabecular Meshwork Cells
by: William Bachman, et al.
Published: (2022-04-01)

Replacement of the Trabecular Meshwork Cells—A Way Ahead in IOP Control?
by: Xiaochen Fan, et al.
Published: (2021-09-01)

Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma
by: Nozomi Igarashi, et al.
Published: (2021-06-01)

Safety and Efficiency of Trabectome-mediated Trabecular Meshwork Ablation for Chinese Glaucoma Patients: A Two-year, Retrospective, Multicentre Study
by: Ya-Long Dang, et al.
Published: (2018-01-01)

Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells
by: Fiona S. McDonnell, et al.
Published: (2023-10-01)

The Effects of Cannabidiol on Aqueous Humor Outflow and Trabecular Meshwork Cell Signaling
by: Alyssa S. Aebersold, et al.
Published: (2022-09-01)

Global and Comparative Proteome Signatures in the Lens Capsule, Trabecular Meshwork, and Iris of Patients With Pseudoexfoliation Glaucoma
by: Prity Sahay, et al.
Published: (2022-04-01)

Myocilin Gene Mutation Induced Autophagy Activation Causes Dysfunction of Trabecular Meshwork Cells
by: Xuejing Yan, et al.
Published: (2022-05-01)

A 3D Model of Human Trabecular Meshwork for the Research Study of Glaucoma
by: Sara Tirendi, et al.
Published: (2020-12-01)

Expressional and functional involvement of gap junctions in aqueous humor outflow into the ocular trabecular meshwork of the anterior chamber
by: Hongxia, et al.
Published: (2019-04-01)

Cathepsin B Localizes in the Caveolae and Participates in the Proteolytic Cascade in Trabecular Meshwork Cells. Potential New Drug Target for the Treatment of Glaucoma
by: April Nettesheim, et al.
Published: (2020-12-01)

Bioinformatics-Based Screening of Key LncRNAs for Modulating the Transcriptome Associated with Glaucoma in Human Trabecular Meshwork Cells
by: Junhong Guo, et al.
Published: (2024-02-01)

The Dual Effect of Rho-Kinase Inhibition on Trabecular Meshwork Cells Cytoskeleton and Extracellular Matrix in an In Vitro Model of Glaucoma
by: Juliette Buffault, et al.
Published: (2022-02-01)