Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report

Orientia tsutsugumashi ( erstwhile Rickettsia tsutsugumashi) is an obligate intracellular bacteria that is showing re-emergence in the last decade in eastern India 1-3. Commonly it causes acute febrile illness with rash and multiple organ involvement including CNS - In fact, Scrub encephalopathy has...

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Main Authors: Sampurna Chowdhury, Rishav Mukherjee, Pradip Kumar Sinha
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2020-06-01
Series:Asian Journal of Medical Sciences
Subjects:
Online Access:https://www.nepjol.info/index.php/AJMS/article/view/28895
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author Sampurna Chowdhury
Rishav Mukherjee
Pradip Kumar Sinha
author_facet Sampurna Chowdhury
Rishav Mukherjee
Pradip Kumar Sinha
author_sort Sampurna Chowdhury
collection DOAJ
description Orientia tsutsugumashi ( erstwhile Rickettsia tsutsugumashi) is an obligate intracellular bacteria that is showing re-emergence in the last decade in eastern India 1-3. Commonly it causes acute febrile illness with rash and multiple organ involvement including CNS - In fact, Scrub encephalopathy has become a common cause of AES in recent times. Although pathogenesis of Scrub typhus is still uncertain, research on other Rickettsiales suggest infection of endothelial cells and vascular dysfunction to be the main mechanism. Based on that pathology we report two very rare manifestations - Acute Ischaemic Stroke and DVT in a single patient of Scrub typhus, occurring simultaneously. No such simultaneous occurrence has been reported in literature till date.
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spelling doaj.art-09d9b806801e40aea4c595697ff9aaef2022-12-21T23:58:06ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762020-06-011149193https://doi.org/10.3126/ajms.v11i4.28895Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case reportSampurna Chowdhury 0https://orcid.org/0000-0002-5010-7565Rishav Mukherjee 1https://orcid.org/0000-0001-5883-2908Pradip Kumar Sinha2Post Graduate Trainee, Department of General Medicine, Medical College, Kolkata Post Graduate Trainee, Department of General Medicine, Medical College, Kolkata Professor and Head, Department of General Medicine, Medical College, KolkataOrientia tsutsugumashi ( erstwhile Rickettsia tsutsugumashi) is an obligate intracellular bacteria that is showing re-emergence in the last decade in eastern India 1-3. Commonly it causes acute febrile illness with rash and multiple organ involvement including CNS - In fact, Scrub encephalopathy has become a common cause of AES in recent times. Although pathogenesis of Scrub typhus is still uncertain, research on other Rickettsiales suggest infection of endothelial cells and vascular dysfunction to be the main mechanism. Based on that pathology we report two very rare manifestations - Acute Ischaemic Stroke and DVT in a single patient of Scrub typhus, occurring simultaneously. No such simultaneous occurrence has been reported in literature till date.https://www.nepjol.info/index.php/AJMS/article/view/28895scrub typhusstrokedvtdoxycycline
spellingShingle Sampurna Chowdhury
Rishav Mukherjee
Pradip Kumar Sinha
Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report
Asian Journal of Medical Sciences
scrub typhus
stroke
dvt
doxycycline
title Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report
title_full Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report
title_fullStr Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report
title_full_unstemmed Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report
title_short Novel occurrence of Acute Ischaemic Stroke and DVT simultaneously in a patient of Scrub Typhus: A Case report
title_sort novel occurrence of acute ischaemic stroke and dvt simultaneously in a patient of scrub typhus a case report
topic scrub typhus
stroke
dvt
doxycycline
url https://www.nepjol.info/index.php/AJMS/article/view/28895
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AT rishavmukherjee noveloccurrenceofacuteischaemicstrokeanddvtsimultaneouslyinapatientofscrubtyphusacasereport
AT pradipkumarsinha noveloccurrenceofacuteischaemicstrokeanddvtsimultaneouslyinapatientofscrubtyphusacasereport