A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause Symptoms
Background and Objective: More than 80% of women experience physical, vasomotor, sexual and psychological symptoms after menopause, and in 10-20% of women, the severity of menopause symptoms affects their quality of life. Due to the complications of using chemical drugs, this study was conducted to...
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2023-03-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| Subjects: | |
| Online Access: | http://jbums.org/article-1-11306-en.pdf |
| _version_ | 1827397623204544512 |
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| author | RM Aftan MK Abdulridha B Abd al-Jbori |
| author_facet | RM Aftan MK Abdulridha B Abd al-Jbori |
| author_sort | RM Aftan |
| collection | DOAJ |
| description | Background and Objective: More than 80% of women experience physical, vasomotor, sexual and psychological symptoms after menopause, and in 10-20% of women, the severity of menopause symptoms affects their quality of life. Due to the complications of using chemical drugs, this study was conducted to compare the effectiveness of evening primrose oil and soybean oil in postmenopausal women.
Methods: In this randomized controlled prospective study, 40 postmenopausal women were assigned into two groups of 20, 500 mg of evening primrose oil and 233 mg of soybean oil extract twice a day for 8 weeks. Measurement of serum hormones (follicle stimulating hormone, luteinizing hormone, estradiol), lipid profile, fasting blood glucose, and high sensitivity C-reactive protein were performed. Moreover, menopausal symptoms were analyzed and compared based on the evaluation score of menopausal symptoms (range 0-3).
Findings: The mean age of women was (51.65±3.7) years. After 2 months of treatment with evening primrose oil, there was a decrease in follicle stimulating hormone, luteinizing hormone levels concurred with increase in estradiol levels (-10.64%) (-8.09%) (7.47%), respectively (p<0.05). Meanwhile, women receiving the soybean oil revealed increase in all the three hormones (5.77%) (12.73%) (13.39%), respectively (p<0.05). Total cholesterol and triglycerides decreased in both study groups after treatment (p<0.05), fasting blood glucose level decreased in group 1 only (-1.39%), and high sensitivity C-reactive protein decreased in group 2 only (-22.33%) (p<0.05). In both groups, women presented with mild to moderate pre-treatment menopausal symptoms (Menopause Symptom Assessment score ranging from 0.75 to 2.25) showed significant decrease in their score up to no symptoms in each study group after 2 months (less than 0.75) (p<0.01).
Conclusion: The results of the study showed that both evening primrose oil and soybean oil supplements improve menopausal symptoms. |
| first_indexed | 2024-03-08T19:12:13Z |
| format | Article |
| id | doaj.art-09df5d9b5e3b4befbe8f27f190936b32 |
| institution | Directory Open Access Journal |
| issn | 1561-4107 2251-7170 |
| language | English |
| last_indexed | 2024-03-08T19:12:13Z |
| publishDate | 2023-03-01 |
| publisher | Babol University of Medical Sciences |
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| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| spelling | doaj.art-09df5d9b5e3b4befbe8f27f190936b322023-12-27T10:07:40ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702023-03-01251305315A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause SymptomsRM Aftan0MK Abdulridha1B Abd al-Jbori2 1.Department of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq. 1.Department of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq. 2.Karbala Holy Health Directorate, Karbala, Iraq. Background and Objective: More than 80% of women experience physical, vasomotor, sexual and psychological symptoms after menopause, and in 10-20% of women, the severity of menopause symptoms affects their quality of life. Due to the complications of using chemical drugs, this study was conducted to compare the effectiveness of evening primrose oil and soybean oil in postmenopausal women. Methods: In this randomized controlled prospective study, 40 postmenopausal women were assigned into two groups of 20, 500 mg of evening primrose oil and 233 mg of soybean oil extract twice a day for 8 weeks. Measurement of serum hormones (follicle stimulating hormone, luteinizing hormone, estradiol), lipid profile, fasting blood glucose, and high sensitivity C-reactive protein were performed. Moreover, menopausal symptoms were analyzed and compared based on the evaluation score of menopausal symptoms (range 0-3). Findings: The mean age of women was (51.65±3.7) years. After 2 months of treatment with evening primrose oil, there was a decrease in follicle stimulating hormone, luteinizing hormone levels concurred with increase in estradiol levels (-10.64%) (-8.09%) (7.47%), respectively (p<0.05). Meanwhile, women receiving the soybean oil revealed increase in all the three hormones (5.77%) (12.73%) (13.39%), respectively (p<0.05). Total cholesterol and triglycerides decreased in both study groups after treatment (p<0.05), fasting blood glucose level decreased in group 1 only (-1.39%), and high sensitivity C-reactive protein decreased in group 2 only (-22.33%) (p<0.05). In both groups, women presented with mild to moderate pre-treatment menopausal symptoms (Menopause Symptom Assessment score ranging from 0.75 to 2.25) showed significant decrease in their score up to no symptoms in each study group after 2 months (less than 0.75) (p<0.01). Conclusion: The results of the study showed that both evening primrose oil and soybean oil supplements improve menopausal symptoms.http://jbums.org/article-1-11306-en.pdfpostmenopausal related symptomsevening primrose oilsoybean oilmenopause symptom assessment (msa) scorebiochemical measures. |
| spellingShingle | RM Aftan MK Abdulridha B Abd al-Jbori A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause Symptoms Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul postmenopausal related symptoms evening primrose oil soybean oil menopause symptom assessment (msa) score biochemical measures. |
| title | A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause Symptoms |
| title_full | A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause Symptoms |
| title_fullStr | A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause Symptoms |
| title_full_unstemmed | A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause Symptoms |
| title_short | A Comparison between the Effects of Evening Primrose Oil and Soybean Oil on Menopause Symptoms |
| title_sort | comparison between the effects of evening primrose oil and soybean oil on menopause symptoms |
| topic | postmenopausal related symptoms evening primrose oil soybean oil menopause symptom assessment (msa) score biochemical measures. |
| url | http://jbums.org/article-1-11306-en.pdf |
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