Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand
Primary mucosal melanoma is a rare, aggressive neoplasm and there is limited data in Asian. We aim is to describe the clinicopathologic features and to evaluate overall survival rate (OS). We reviewed 17 cases over a 10-year period. The mean age was 60.9 ± 14.8 with 94.1% being female. The female ge...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2018-09-01
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Series: | Dermatologica Sinica |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1027811717302124 |
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author | Kumpol Aiempanakit Kanokphorn Chiratikarnwong Sauvarat Auepemkiate Hutcha Sriplung |
author_facet | Kumpol Aiempanakit Kanokphorn Chiratikarnwong Sauvarat Auepemkiate Hutcha Sriplung |
author_sort | Kumpol Aiempanakit |
collection | DOAJ |
description | Primary mucosal melanoma is a rare, aggressive neoplasm and there is limited data in Asian. We aim is to describe the clinicopathologic features and to evaluate overall survival rate (OS). We reviewed 17 cases over a 10-year period. The mean age was 60.9 ± 14.8 with 94.1% being female. The female genital tract was the principal location (52.9%). The most presenting symptoms were masses (88.2%), with 44.1% being amelanotic melanoma. The majority of patients (41.2%) had TNM stage IV. The median OS was 19.5 months, whilst the 1- and 3-year OS were; 70.6% (95% CI, 51.9–95.9%) and 9.8% (95% CI, 1.6–59.5%), respectively. Keywords: Anorectal, Female genital tract, Head and neck, Primary mucosal melanoma, Survival outcome |
first_indexed | 2024-12-11T00:43:43Z |
format | Article |
id | doaj.art-09e5541ce7c549e2b91724c43debdd20 |
institution | Directory Open Access Journal |
issn | 1027-8117 |
language | English |
last_indexed | 2024-12-11T00:43:43Z |
publishDate | 2018-09-01 |
publisher | Wolters Kluwer Medknow Publications |
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series | Dermatologica Sinica |
spelling | doaj.art-09e5541ce7c549e2b91724c43debdd202022-12-22T01:26:50ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172018-09-01363140142Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in ThailandKumpol Aiempanakit0Kanokphorn Chiratikarnwong1Sauvarat Auepemkiate2Hutcha Sriplung3Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand; Corresponding author. Division of Dermatology, Department of Internal Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand. Fax +66 74429385.Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandDepartment of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandEpidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandPrimary mucosal melanoma is a rare, aggressive neoplasm and there is limited data in Asian. We aim is to describe the clinicopathologic features and to evaluate overall survival rate (OS). We reviewed 17 cases over a 10-year period. The mean age was 60.9 ± 14.8 with 94.1% being female. The female genital tract was the principal location (52.9%). The most presenting symptoms were masses (88.2%), with 44.1% being amelanotic melanoma. The majority of patients (41.2%) had TNM stage IV. The median OS was 19.5 months, whilst the 1- and 3-year OS were; 70.6% (95% CI, 51.9–95.9%) and 9.8% (95% CI, 1.6–59.5%), respectively. Keywords: Anorectal, Female genital tract, Head and neck, Primary mucosal melanoma, Survival outcomehttp://www.sciencedirect.com/science/article/pii/S1027811717302124 |
spellingShingle | Kumpol Aiempanakit Kanokphorn Chiratikarnwong Sauvarat Auepemkiate Hutcha Sriplung Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand Dermatologica Sinica |
title | Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand |
title_full | Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand |
title_fullStr | Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand |
title_full_unstemmed | Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand |
title_short | Clinicopathologic characteristics and survival outcomes of primary mucosal melanomas: A 10-year retrospective analysis from a single tertiary medical center in Thailand |
title_sort | clinicopathologic characteristics and survival outcomes of primary mucosal melanomas a 10 year retrospective analysis from a single tertiary medical center in thailand |
url | http://www.sciencedirect.com/science/article/pii/S1027811717302124 |
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