Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching Points
Sarcoidosis with manifest cardiac involvement typically presents with heart failure, conduction abnormalities, or ventricular arrhythmias. Here, we present a case of a young woman whose presentation raised suspicion for metastatic cardiac disease of unknown primary origin. Further investigation reve...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-04-01
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| Series: | CJC Open |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589790X21003589 |
| _version_ | 1818495186357977088 |
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| author | Ramsey G.G. Powell, MD Frédéric L. Paulin, MD Jeffrey Flemming, MD Scott Harris, MD Stephen A. Duffett, MD |
| author_facet | Ramsey G.G. Powell, MD Frédéric L. Paulin, MD Jeffrey Flemming, MD Scott Harris, MD Stephen A. Duffett, MD |
| author_sort | Ramsey G.G. Powell, MD |
| collection | DOAJ |
| description | Sarcoidosis with manifest cardiac involvement typically presents with heart failure, conduction abnormalities, or ventricular arrhythmias. Here, we present a case of a young woman whose presentation raised suspicion for metastatic cardiac disease of unknown primary origin. Further investigation revealed cardiac sarcoidosis with multiple intramyocardial granulomatous masses in the absence of significant enlargement of hilar or mediastinal nodes. This case highlights the following: (i) sarcoidosis can mimic metastatic cardiac tumours; and (ii) hilar and mediastinal lymph nodes can be metabolically active in cardiac sarcoidosis in the absence of significant enlargement. Résumé: La sarcoïdose avec atteinte cardiaque patente se manifeste typiquement par une insuffisance cardiaque, des troubles de la conduction ou des arythmies ventriculaires. Nous présentons ici le cas d’une jeune femme dont le tableau clinique évoquait une pathologie cardiaque métastatique d’origine primitive inconnue. Des examens supplémentaires ont révélé une sarcoïdose cardiaque associée à de multiples granulomes intramyocardiques, en l’absence d’hypertrophie importante des ganglions hilaires ou médiastinaux. Ce cas illustre les points suivants : (i) les symptômes de la sarcoïdose peuvent imiter ceux de tumeurs cardiaques métastatiques; et (ii) les ganglions lymphatiques hilaires et médiastinaux associés à une sarcoïdose cardiaque peuvent présenter une activité métabolique en l’absence d’hypertrophie importante. |
| first_indexed | 2024-12-10T18:17:09Z |
| format | Article |
| id | doaj.art-09e7a25c931d431f8347a88c9d89c962 |
| institution | Directory Open Access Journal |
| issn | 2589-790X |
| language | English |
| last_indexed | 2024-12-10T18:17:09Z |
| publishDate | 2022-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | CJC Open |
| spelling | doaj.art-09e7a25c931d431f8347a88c9d89c9622022-12-22T01:38:18ZengElsevierCJC Open2589-790X2022-04-0144432434Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching PointsRamsey G.G. Powell, MD0Frédéric L. Paulin, MD1Jeffrey Flemming, MD2Scott Harris, MD3Stephen A. Duffett, MD4Department of Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland, CanadaDepartment of Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland, CanadaDepartment of Nuclear and Molecular Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland, CanadaDepartment of Radiology, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland, CanadaDepartment of Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada; Corresponding author: Dr Stephen A. Duffett, Division of Cardiology, Department of Medicine, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Phillip Dr, St. John's, Newfoundland A1B 3V6, Canada. Tel.: +1-709-777-6300; fax: +1 709-726-1028.Sarcoidosis with manifest cardiac involvement typically presents with heart failure, conduction abnormalities, or ventricular arrhythmias. Here, we present a case of a young woman whose presentation raised suspicion for metastatic cardiac disease of unknown primary origin. Further investigation revealed cardiac sarcoidosis with multiple intramyocardial granulomatous masses in the absence of significant enlargement of hilar or mediastinal nodes. This case highlights the following: (i) sarcoidosis can mimic metastatic cardiac tumours; and (ii) hilar and mediastinal lymph nodes can be metabolically active in cardiac sarcoidosis in the absence of significant enlargement. Résumé: La sarcoïdose avec atteinte cardiaque patente se manifeste typiquement par une insuffisance cardiaque, des troubles de la conduction ou des arythmies ventriculaires. Nous présentons ici le cas d’une jeune femme dont le tableau clinique évoquait une pathologie cardiaque métastatique d’origine primitive inconnue. Des examens supplémentaires ont révélé une sarcoïdose cardiaque associée à de multiples granulomes intramyocardiques, en l’absence d’hypertrophie importante des ganglions hilaires ou médiastinaux. Ce cas illustre les points suivants : (i) les symptômes de la sarcoïdose peuvent imiter ceux de tumeurs cardiaques métastatiques; et (ii) les ganglions lymphatiques hilaires et médiastinaux associés à une sarcoïdose cardiaque peuvent présenter une activité métabolique en l’absence d’hypertrophie importante.http://www.sciencedirect.com/science/article/pii/S2589790X21003589 |
| spellingShingle | Ramsey G.G. Powell, MD Frédéric L. Paulin, MD Jeffrey Flemming, MD Scott Harris, MD Stephen A. Duffett, MD Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching Points CJC Open |
| title | Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching Points |
| title_full | Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching Points |
| title_fullStr | Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching Points |
| title_full_unstemmed | Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching Points |
| title_short | Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old WomanNovel Teaching Points |
| title_sort | multiple intramyocardial masses in an otherwise healthy 35 year old womannovel teaching points |
| url | http://www.sciencedirect.com/science/article/pii/S2589790X21003589 |
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