Antibiotic resistome in groundwater and its association with mountain springs and river
The distribution of antibiotic resistance genes (ARGs) in water sources potentially threatens drinking water safety. However, the sources of antibiotic resistome in groundwater are still under-investigated. Here, we evaluated the profiles of antibiotic resistome in peri-urban groundwater and its ass...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Ecotoxicology and Environmental Safety |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651323001070 |
| _version_ | 1828012083342475264 |
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| author | Fu-Yi Huang Yi Zhao Roy Neilson Xin-Yuan Zhou Hu Li Lei Ding Shu-Yi-Dan Zhou Jian-Qiang Su |
| author_facet | Fu-Yi Huang Yi Zhao Roy Neilson Xin-Yuan Zhou Hu Li Lei Ding Shu-Yi-Dan Zhou Jian-Qiang Su |
| author_sort | Fu-Yi Huang |
| collection | DOAJ |
| description | The distribution of antibiotic resistance genes (ARGs) in water sources potentially threatens drinking water safety. However, the sources of antibiotic resistome in groundwater are still under-investigated. Here, we evaluated the profiles of antibiotic resistome in peri-urban groundwater and its associated water sources (river and mountain spring) to characterize the antibiotic resistome from natural water sources on groundwater resistome. A total of 261 antibiotic resistome were detected in groundwater, mountain spring, and river samples. The relative abundances of ARGs and mobile genetic elements (MGEs) were significantly higher in the river samples than in spring water and groundwater samples. The resistome profiles were similar between groundwater and spring water but differed from the river samples. According to source tracking results, the groundwater resistome was likely to be derived from springs (28.0%−50.0%) and rivers (28.6%−48.6%), which share the same trend for the source tracking of bacterial communities. Bacterial α-diversity, bacterial β-diversity, and MGEs directly or indirectly affected the ARGs in groundwater samples. Although the abundance of groundwater resistome was not elevated by river and spring water, groundwater resistomes were diverse and may be derived from both river and spring water. We highlight the importance of groundwater resistome and its association with potential water sources, providing a better understanding and basis for the effective control of the ARG proliferation and dissemination in groundwater from exogenous water bodies in the future. |
| first_indexed | 2024-04-10T09:25:00Z |
| format | Article |
| id | doaj.art-09ec7fbebb39465da231d7d8e824877c |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-04-10T09:25:00Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-09ec7fbebb39465da231d7d8e824877c2023-02-20T04:08:39ZengElsevierEcotoxicology and Environmental Safety0147-65132023-03-01252114603Antibiotic resistome in groundwater and its association with mountain springs and riverFu-Yi Huang0Yi Zhao1Roy Neilson2Xin-Yuan Zhou3Hu Li4Lei Ding5Shu-Yi-Dan Zhou6Jian-Qiang Su7Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China; University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, ChinaSchool of Water Resources and Environment, China University of Geosciences (Beijing), Beijing 100083, ChinaEcological Sciences, The James Hutton Institute, Dundee DD2 5DA, Scotland, UKKey Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China; University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, ChinaKey Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China; University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, ChinaDepartment of Mathematical and Statistical Sciences, University of Alberta, Edmonton, Alberta, CanadaKey Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China; Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems, South China Botanical Garden, Chinese Academy of Sciences, 723 Xingke Road, Tianhe District, Guangzhou 510650, China; University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, China; Corresponding author at: Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems, South China Botanical Garden, Chinese Academy of Sciences, 723 Xingke Road, Tianhe District, Guangzhou 510650, China.Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen 361021, China; University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, ChinaThe distribution of antibiotic resistance genes (ARGs) in water sources potentially threatens drinking water safety. However, the sources of antibiotic resistome in groundwater are still under-investigated. Here, we evaluated the profiles of antibiotic resistome in peri-urban groundwater and its associated water sources (river and mountain spring) to characterize the antibiotic resistome from natural water sources on groundwater resistome. A total of 261 antibiotic resistome were detected in groundwater, mountain spring, and river samples. The relative abundances of ARGs and mobile genetic elements (MGEs) were significantly higher in the river samples than in spring water and groundwater samples. The resistome profiles were similar between groundwater and spring water but differed from the river samples. According to source tracking results, the groundwater resistome was likely to be derived from springs (28.0%−50.0%) and rivers (28.6%−48.6%), which share the same trend for the source tracking of bacterial communities. Bacterial α-diversity, bacterial β-diversity, and MGEs directly or indirectly affected the ARGs in groundwater samples. Although the abundance of groundwater resistome was not elevated by river and spring water, groundwater resistomes were diverse and may be derived from both river and spring water. We highlight the importance of groundwater resistome and its association with potential water sources, providing a better understanding and basis for the effective control of the ARG proliferation and dissemination in groundwater from exogenous water bodies in the future.http://www.sciencedirect.com/science/article/pii/S0147651323001070Hyporheic zonePeri-urbanSource trackingARGsWater source |
| spellingShingle | Fu-Yi Huang Yi Zhao Roy Neilson Xin-Yuan Zhou Hu Li Lei Ding Shu-Yi-Dan Zhou Jian-Qiang Su Antibiotic resistome in groundwater and its association with mountain springs and river Ecotoxicology and Environmental Safety Hyporheic zone Peri-urban Source tracking ARGs Water source |
| title | Antibiotic resistome in groundwater and its association with mountain springs and river |
| title_full | Antibiotic resistome in groundwater and its association with mountain springs and river |
| title_fullStr | Antibiotic resistome in groundwater and its association with mountain springs and river |
| title_full_unstemmed | Antibiotic resistome in groundwater and its association with mountain springs and river |
| title_short | Antibiotic resistome in groundwater and its association with mountain springs and river |
| title_sort | antibiotic resistome in groundwater and its association with mountain springs and river |
| topic | Hyporheic zone Peri-urban Source tracking ARGs Water source |
| url | http://www.sciencedirect.com/science/article/pii/S0147651323001070 |
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