Information management for enabling systems medicine

Systems medicine is a data-oriented approach in research and clinical practice to support study and treatment of complex diseases. It relies on well-defined information management processes providing comprehensive and up to date information as basis for electronic decision support. The authors sugge...

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Main Authors: Ganzinger Matthias, Knaup Petra
Format: Article
Language:English
Published: De Gruyter 2017-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2017-0105
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author Ganzinger Matthias
Knaup Petra
author_facet Ganzinger Matthias
Knaup Petra
author_sort Ganzinger Matthias
collection DOAJ
description Systems medicine is a data-oriented approach in research and clinical practice to support study and treatment of complex diseases. It relies on well-defined information management processes providing comprehensive and up to date information as basis for electronic decision support. The authors suggest a three-layer information technology (IT) architecture for systems medicine and a cyclic data management approach including a knowledge base that is dynamically updated by extract, transform, and load (ETL) procedures. Decision support is suggested as case-based and rule-based components. Results are presented via a user interface to acknowledging clinical requirements in terms of time and complexity. The systems medicine application was implemented as a prototype.
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spelling doaj.art-09ed2794b403428a880548abc7eecd522023-04-11T17:07:14ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042017-09-013250150410.1515/cdbme-2017-0105cdbme-2017-0105Information management for enabling systems medicineGanzinger Matthias0Knaup Petra1Heidelberg University, Institute of Medical Biometry and Informatics, Im Neuenheimer Feld 130.3, 69120 Heidelberg, GermanyHeidelberg University, Institute of Medical Biometry and Informatics, Im Neuenheimer Feld 130.3, 69120 Heidelberg, GermanySystems medicine is a data-oriented approach in research and clinical practice to support study and treatment of complex diseases. It relies on well-defined information management processes providing comprehensive and up to date information as basis for electronic decision support. The authors suggest a three-layer information technology (IT) architecture for systems medicine and a cyclic data management approach including a knowledge base that is dynamically updated by extract, transform, and load (ETL) procedures. Decision support is suggested as case-based and rule-based components. Results are presented via a user interface to acknowledging clinical requirements in terms of time and complexity. The systems medicine application was implemented as a prototype.https://doi.org/10.1515/cdbme-2017-0105systems medicineinformation managementdecision support systems
spellingShingle Ganzinger Matthias
Knaup Petra
Information management for enabling systems medicine
Current Directions in Biomedical Engineering
systems medicine
information management
decision support systems
title Information management for enabling systems medicine
title_full Information management for enabling systems medicine
title_fullStr Information management for enabling systems medicine
title_full_unstemmed Information management for enabling systems medicine
title_short Information management for enabling systems medicine
title_sort information management for enabling systems medicine
topic systems medicine
information management
decision support systems
url https://doi.org/10.1515/cdbme-2017-0105
work_keys_str_mv AT ganzingermatthias informationmanagementforenablingsystemsmedicine
AT knauppetra informationmanagementforenablingsystemsmedicine