Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells
Objective To explore the risk factors for adverse reactions in patients undergoing apheresis for autologous red blood cells. Methods The clinical data of 756 patients for autologous red blood cells enriched by apheresis in our hospital from January 2019 to December 2020 were collected. Univariate an...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Third Military Medical University
2022-04-01
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| Series: | Di-san junyi daxue xuebao |
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| Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/202201135.htm |
| _version_ | 1818523945554411520 |
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| author | YAO Huan LIU Xiaomin CHI Hongxu ZHANG Yu |
| author_facet | YAO Huan LIU Xiaomin CHI Hongxu ZHANG Yu |
| author_sort | YAO Huan |
| collection | DOAJ |
| description | Objective To explore the risk factors for adverse reactions in patients undergoing apheresis for autologous red blood cells. Methods The clinical data of 756 patients for autologous red blood cells enriched by apheresis in our hospital from January 2019 to December 2020 were collected. Univariate analysis was used to study the influencing factors for adverse reactions in the process of apheresis. Logistic regression analysis was adopted to analyze the risk factors for adverse reactions in apheresis. The differences of blood pressure and heart rate of a same patient at multiple time points were analyzed by generalized estimation equation. Results Among the 756 patients, 59 of them (7.8%) had adverse reactions, including 6.8% vasovagal reaction in Class B and 93.2% citrate reaction in Class C. Univariate analysis showed that gender, age, BMI, body blood volume, treatment duration and systolic blood pressure before treatment had statistical significance (P < 0.05). The results of logistic regression analysis showed that age and body blood volume had effects on adverse reactions in the process of apheresis (OR=0.954, 95%CI: 0.934~0.975; OR=0.356, 95%CI: 0.230~0.551, P < 0.05). Conclusion Younger age and lower blood volume are the risk factors for adverse reactions in the process of apheresis for autologous red blood cell collection. |
| first_indexed | 2024-12-11T05:51:00Z |
| format | Article |
| id | doaj.art-09ed43eb4d69496d85e0a692e0375d7a |
| institution | Directory Open Access Journal |
| issn | 1000-5404 |
| language | zho |
| last_indexed | 2024-12-11T05:51:00Z |
| publishDate | 2022-04-01 |
| publisher | Editorial Office of Journal of Third Military Medical University |
| record_format | Article |
| series | Di-san junyi daxue xuebao |
| spelling | doaj.art-09ed43eb4d69496d85e0a692e0375d7a2022-12-22T01:18:48ZzhoEditorial Office of Journal of Third Military Medical UniversityDi-san junyi daxue xuebao1000-54042022-04-0144884284610.16016/j.2097-0927.202201135Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cellsYAO Huan0LIU Xiaomin1CHI Hongxu2ZHANG Yu3Department of Blood Transfusion, the First Medical Center, Chinese PLA General Hospital, Beijing, 100853Department of Blood Transfusion, the First Medical Center, Chinese PLA General Hospital, Beijing, 100853 Department of Blood Transfusion, the First Medical Center, Chinese PLA General Hospital, Beijing, 100853 Detachment 91, Troop 32296 of PLA, Shenyang, Liaoning Province, 110112, China Objective To explore the risk factors for adverse reactions in patients undergoing apheresis for autologous red blood cells. Methods The clinical data of 756 patients for autologous red blood cells enriched by apheresis in our hospital from January 2019 to December 2020 were collected. Univariate analysis was used to study the influencing factors for adverse reactions in the process of apheresis. Logistic regression analysis was adopted to analyze the risk factors for adverse reactions in apheresis. The differences of blood pressure and heart rate of a same patient at multiple time points were analyzed by generalized estimation equation. Results Among the 756 patients, 59 of them (7.8%) had adverse reactions, including 6.8% vasovagal reaction in Class B and 93.2% citrate reaction in Class C. Univariate analysis showed that gender, age, BMI, body blood volume, treatment duration and systolic blood pressure before treatment had statistical significance (P < 0.05). The results of logistic regression analysis showed that age and body blood volume had effects on adverse reactions in the process of apheresis (OR=0.954, 95%CI: 0.934~0.975; OR=0.356, 95%CI: 0.230~0.551, P < 0.05). Conclusion Younger age and lower blood volume are the risk factors for adverse reactions in the process of apheresis for autologous red blood cell collection.http://aammt.tmmu.edu.cn/Upload/rhtml/202201135.htmapheresis autologous red blood cellsadverse reactionsrisk factorsstrategies for nursing |
| spellingShingle | YAO Huan LIU Xiaomin CHI Hongxu ZHANG Yu Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells Di-san junyi daxue xuebao apheresis autologous red blood cells adverse reactions risk factors strategies for nursing |
| title | Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells |
| title_full | Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells |
| title_fullStr | Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells |
| title_full_unstemmed | Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells |
| title_short | Risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells |
| title_sort | risk factors for adverse reactions in patients after apheresis technology for autologous red blood cells |
| topic | apheresis autologous red blood cells adverse reactions risk factors strategies for nursing |
| url | http://aammt.tmmu.edu.cn/Upload/rhtml/202201135.htm |
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