Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light Source

Blood purification therapy that removes pathogenic substances and unnecessary blood components in blood is performed by extracorporeal circulation therapy that draws blood out of the body. In extracorporeal circulation therapy, blood is filled in the circuit and circulated outside the body by a pump...

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Main Authors: Takahiro Wabe, Ryo Suzuki, Akimitsu Fujii, Yohsuke Uchida
Format: Article
Language:English
Published: IFSA Publishing, S.L. 2022-10-01
Series:Sensors & Transducers
Subjects:
Online Access:https://sensorsportal.com/HTML/DIGEST/october_2022/Vol_259/P_3279.pdf
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author Takahiro Wabe
Ryo Suzuki
Akimitsu Fujii
Yohsuke Uchida
author_facet Takahiro Wabe
Ryo Suzuki
Akimitsu Fujii
Yohsuke Uchida
author_sort Takahiro Wabe
collection DOAJ
description Blood purification therapy that removes pathogenic substances and unnecessary blood components in blood is performed by extracorporeal circulation therapy that draws blood out of the body. In extracorporeal circulation therapy, blood is filled in the circuit and circulated outside the body by a pump, but the blood coagulates due to a foreign body reaction in the circuit. Anticoagulants such as heparin are used as blood coagulation measures, but they are not absolute. There is a need for a measurement method that can be predicted before blood coagulation. Photoacoustic imaging was used for predictive maintenance measurements. In photoacoustic imaging used for extracorporeal circulation therapy, the amount of data used must be reduced because it is constantly measured. Accordingly, in this study, we identified areas where photoacoustic imaging changes significantly over time due to blood coagulation, and reduced the volume of data by limiting the area to be measured to 233 pixels where 218240 pixels are normally required for measurement. In addition, because we were able to identify the measurement site, based on that, we develop a predictive maintenance system based on changes in blood coagulation over time in an extracorporeal blood circulation circuit that simulates the environment of extracorporeal blood circulation therapy.
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spelling doaj.art-09ed86726b2347c2bfdfbc218055a7e12023-08-14T10:27:55ZengIFSA Publishing, S.L.Sensors & Transducers2306-85151726-54792022-10-0125954551Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light SourceTakahiro Wabe0Ryo Suzuki1Akimitsu Fujii2Yohsuke Uchida3Teikyo University of Science, Department of Life & Health Sciences, Faculty of Life & Environmental SciencesFaculty of Pharma-Science, Teikyo UniversityTokyo college of Medico-Pharmaco TechnologyShuto ikoBlood purification therapy that removes pathogenic substances and unnecessary blood components in blood is performed by extracorporeal circulation therapy that draws blood out of the body. In extracorporeal circulation therapy, blood is filled in the circuit and circulated outside the body by a pump, but the blood coagulates due to a foreign body reaction in the circuit. Anticoagulants such as heparin are used as blood coagulation measures, but they are not absolute. There is a need for a measurement method that can be predicted before blood coagulation. Photoacoustic imaging was used for predictive maintenance measurements. In photoacoustic imaging used for extracorporeal circulation therapy, the amount of data used must be reduced because it is constantly measured. Accordingly, in this study, we identified areas where photoacoustic imaging changes significantly over time due to blood coagulation, and reduced the volume of data by limiting the area to be measured to 233 pixels where 218240 pixels are normally required for measurement. In addition, because we were able to identify the measurement site, based on that, we develop a predictive maintenance system based on changes in blood coagulation over time in an extracorporeal blood circulation circuit that simulates the environment of extracorporeal blood circulation therapy.https://sensorsportal.com/HTML/DIGEST/october_2022/Vol_259/P_3279.pdfblood coagulationphotoacoustic imagingledextracorporeal circulation therapypredictive maintenance
spellingShingle Takahiro Wabe
Ryo Suzuki
Akimitsu Fujii
Yohsuke Uchida
Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light Source
Sensors & Transducers
blood coagulation
photoacoustic imaging
led
extracorporeal circulation therapy
predictive maintenance
title Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light Source
title_full Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light Source
title_fullStr Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light Source
title_full_unstemmed Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light Source
title_short Measurement Site Selection and Validation in Extracorporeal Circuit for Predictive Maintenance of Blood Coagulation using Photoacoustic Imaging of LED Light Source
title_sort measurement site selection and validation in extracorporeal circuit for predictive maintenance of blood coagulation using photoacoustic imaging of led light source
topic blood coagulation
photoacoustic imaging
led
extracorporeal circulation therapy
predictive maintenance
url https://sensorsportal.com/HTML/DIGEST/october_2022/Vol_259/P_3279.pdf
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AT ryosuzuki measurementsiteselectionandvalidationinextracorporealcircuitforpredictivemaintenanceofbloodcoagulationusingphotoacousticimagingofledlightsource
AT akimitsufujii measurementsiteselectionandvalidationinextracorporealcircuitforpredictivemaintenanceofbloodcoagulationusingphotoacousticimagingofledlightsource
AT yohsukeuchida measurementsiteselectionandvalidationinextracorporealcircuitforpredictivemaintenanceofbloodcoagulationusingphotoacousticimagingofledlightsource