CRISPR/Cas9-mediated genome editing in nonhuman primates
Owing to their high similarity to humans, non-human primates (NHPs) provide an exceedingly suitable model for the study of human disease. In this Review, we summarize the history of transgenic NHP models and the progress of CRISPR/Cas9-mediated genome editing in NHPs, from the first proof-of-princip...
Main Authors: | Yu Kang, Chu Chu, Fang Wang, Yuyu Niu |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2019-10-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/12/10/dmm039982 |
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