SYNTHESIS AND ANALGETIC ACTIVITY EVALUATION OF 4-[N-(4-HYDROXYPHENYL)CARBOXYMIDOYL]-2-METHOXYPHENOL

SYNTHESIS AND ANALGETIC ACTIVITY EVALUATION OF 4-[N-(4-HYDROXYPHENYL)CARBOXYMIDOYL]-2-METHOXYPHENOL

Paracetamol is an analgesic-antipyretic compound derived from p-aminophenol. Though paracetamol has good efficacy and safety on consumption, parasetamol has hepatotoxic effect as its adverse drug reaction. 4-[N-(4-hydroxyphenyl)carboxymidoyl]-2-methoxyphenol is one of p-aminophenol derivative th...

Full description

Bibliographic Details
Main Authors:	Pudjono, Jessica Anindita, Arief Rahman Hakim, Hari Purnomo
Format:	Article
Language:	English
Published:	Universitas Gadjah Mada 2016-04-01
Series:	Indonesian Journal of Pharmacy
Subjects:	4-[N-(4-hydroxyphenyl)carboxymidoyl]-2-methoxyphenol p-aminophenol analgesic writhing test
Online Access:	http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1064

Similar Items

A study of 2-, 3- and 4-methoxyphenol hydrogenation and hydrodeoxygenation over Rh/silica using deuterium
by: Sofia Papaleonidopoulou, et al.
Published: (2023-06-01)

CATALYTIC ACTIVITY CoMo/USY ON DEOXYGENATION REACTION OF 4-METHOXYPHENOL IN BATCH REACTOR
by: Khoirina Dwi Nugrahaningtyas, et al.
Published: (2017-03-01)

4-Allyl-2-methoxyphenol modulates the expression of genes involved in efflux pump, biofilm formation and sterol biosynthesis in azole resistant Aspergillus fumigatus
by: Pooja Sen, et al.
Published: (2023-02-01)

4-{[(4-Methoxyphenyl)imino]methyl}-3-hydroxyphenyl 4-(Hexadecanoyloxy)benzoate
by: Peng-Lim Boey, et al.
Published: (2012-04-01)

A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose
by: Wanna Eiamart, et al.
Published: (2022-01-01)

Anti-inflammatory effects of methoxyphenolic compounds on human airway cells
by: Houser Kenneth R, et al.
Published: (2012-03-01)

Identification of 3-((4-Hydroxyphenyl)amino)propanoic Acid Derivatives as Anticancer Candidates with Promising Antioxidant Properties
by: Povilas Kavaliauskas, et al.
Published: (2024-06-01)

Synthesis of 3-((4-Hydroxyphenyl)amino)propanoic Acid Derivatives as Promising Scaffolds for the Development of Antimicrobial Candidates Targeting Multidrug-Resistant Bacterial and Fungal Pathogens
by: Povilas Kavaliauskas, et al.
Published: (2024-02-01)

A novel O-methyltransferase Cp4MP-OMT catalyses the final step in the biosynthesis of the volatile 1,4-dimethoxybenzene in pumpkin (Cucurbita pepo) flowers
by: Marion Christine Hoepflinger, et al.
Published: (2024-04-01)

Novel Metal Coordination Complexes Based on 4-Aminophenol: Spectroscopic Analysis and Antibacterial Test
by: Husna Syaima, et al.
Published: (2023-04-01)

Metabolism of 4-chloro-2-nitrophenol in a Gram-positive bacterium, <it>Exiguobacterium</it> sp. PMA
by: Arora Pankaj, et al.
Published: (2012-11-01)

Preparation and Biological Evaluation of [111In]-THPP [5, 10, 15, 20-tetrakis (4-Hydroxyphenyl) Porphyrin] Complex in Healthy Rats Via SPECT Imaging
by: A.R Jalilian, et al.
Published: (2016-11-01)

Increased In Vivo Exposure of N-(4-Hydroxyphenyl) Retinamide (4-HPR) to Achieve Plasma Concentrations Effective against Dengue Virus
by: Alexander J. Martin, et al.
Published: (2023-07-01)

A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models
by: Lalit Kanodia, et al.
Published: (2009-06-01)

Photocatalytic reduction of 4-nitrophenol over eco-friendly NixCuxFe2O4 without an additional reducing agent in water
by: Prabhu Azhagapillai, et al.
Published: (2024-01-01)

4-ETOKSI-3-METOKSIFENOL DAN METIL-3,4-DIHIDROKSIBENZOAT, DUA SENYAWA TURUNAN FENOLIK DARI EKSTRAK ETIL ASETAT KULIT UMBI GADUNG (Dioscorea hispida Dennst) DAN AKTIVITAS ANTIOKSIDAN EKSTRAK ETIL ASETAT
by: Nanik Siti Aminah, et al.
Published: (2018-07-01)

Synthesis, Characterization and Antioxidant Study of Some Metal Ion Complexes with Azo 1-(2,4,6-trihydroxy-3-((3-hydroxyphenyl) diazenyl) phenyl) Ethan-1-one.
by: Areeg Malek Fadhel, et al.
Published: (2024-12-01)

Multitargeted molecular modelling of alginic acid modified with 4-aminophenol dopped with silver nanoparticles as a potent cytotoxic agent
by: Haneen A. Mahmoud, et al.
Published: (2023-06-01)

SYNTHESIS AND ANTITUMOR ACTIVITY OF COPPER, NICKEL AND COBALT COORDINATION COMPOUNDS WITH 1-(2-HYDROXYPHENYL)ETHANONE N(4)-ALLYL-3-THIOSEMICARBAZONE
by: Vasilii GRAUR, et al.
Published: (2015-12-01)

The Competition between 4-Nitrophenol Reduction and BH<sub>4</sub><sup>−</sup> Hydrolysis on Metal Nanoparticle Catalysts
by: Shalaka Varshney, et al.
Published: (2023-09-01)

2,2-Bis(4-Hydroxyphenyl)-1-Propanol—A Persistent Product of Bisphenol A Bio-Oxidation in Fortified Environmental Water, as Identified by HPLC/UV/ESI-MS
by: Małgorzata Drzewiecka, et al.
Published: (2021-03-01)

Investigating the Effect of Deactivation Rate Constant of Polymer-Based Silver Catalyst on the Reduction of Pollutant 4-Nitrophenol to 4-Aminophenol
by: Navid Ahadi-Jomairan, et al.
Published: (2024-08-01)

Alleviation Effects of Microbial Metabolites from Resveratrol on Non-Alcoholic Fatty Liver Disease
by: Jingling Guo, et al.
Published: (2022-12-01)

Facile Sonochemical Preparation of Au-ZrO<sub>2</sub> Nanocatalyst for the Catalytic Reduction of 4-Nitrophenol
by: Mohammed Rafi Shaik, et al.
Published: (2020-01-01)

Determination of Impurities in New Promising Antioxidants Bis-[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl]sulfide and Dodecyl(3,5-dimethyl-4-hydroxybenzyl)sulfide
by: T. G. Shinko, et al.
Published: (2022-02-01)

Organic Salts of Pharmaceutical Impurity <i>p</i>-Aminophenol
by: U. B. Rao Khandavilli, et al.
Published: (2020-04-01)

Electrochemical oxidation of 4-amino phenol in the presence of 2-mercaptobenzimidazoles and synthesis of new organosulfur compounds
by: Ameneh Amani, et al.
Published: (2021-09-01)

Development of an Efficient Voltammetric Sensor for the Monitoring of 4-Aminophenol Based on Flexible Laser Induced Graphene Electrodes Modified with MWCNT-PANI
by: Salem Nasraoui, et al.
Published: (2022-01-01)

ESIPT-Capable 4-(2-Hydroxyphenyl)-2-(Pyridin-2-yl)-1<i>H</i>-Imidazoles with Single and Double Proton Transfer: Synthesis, Selective Reduction of the Imidazolic OH Group and Luminescence
by: Nikita A. Shekhovtsov, et al.
Published: (2023-02-01)

Data on microRNA expression, predicted gene targets and pathway analysis in response to different concentrations of a cranberry proanthocyanidin-rich extract and its metabolite 3-(4-hydroxyphenyl)-propionic acid in intestinal Caco-2BBe1 cells
by: Zoe Dimoff, et al.
Published: (2024-06-01)

A Comparison of efficiency of (AMP) and its derivative (AMPAA) against some pathogenic bacteria
by: Suzan S. Hussain
Published: (2018-04-01)

Synthesis of Chiral 1,4,2-Oxazaphosphepines
by: Oscar Salgado-Escobar, et al.
Published: (2015-07-01)

A study on 2-(2’-hydroxyphenyl) benzoxazoles derivatives as potential organic UV filters, Part I
by: Jâmeson Ferreira da Silva, et al.
Published: (2023-02-01)

Cocrystal of Ibuprofen–Nicotinamide: Solid-State Characterization and In Vivo Analgesic Activity Evaluation
by: Yori Yuliandra, et al.
Published: (2018-06-01)

Anti-inflammatory and anti-nociceptive properties offractionated extracts in different parts of Sambucus ebulus
by: S. Saiednia, et al.
Published: (2006-01-01)

Comparative analysis of analgesic and anti-inflammatory activity of bark and leaves of Acacia ferruginea DC.
by: Samriti Faujdar, et al.
Published: (2016-03-01)

Voltammetric sensor based on a Ni-Co-layered double hydroxide/multi-walled carbon nanotubes nanocomposite for 4-aminophenol determination
by: Somayeh Tajik, et al.
Published: (2024-06-01)

In vivo analgesic, antipyretic, and anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic extract from Litsea glutinosaleaves
by: Rumpa Bhowmick, et al.
Published: (2014-01-01)

Clinical Evaluation of Analgesic Activity of Guduchi (Tinospora Cordifolia) Using Animal Model
by: Bhomik Goel, et al.
Published: (2014-08-01)

Safety assessment of diethyl[[3,5‐bis(1,1‐dimethylethyl)‐4‐hydroxyphenyl]methyl] phosphonate for use in a food contact material
by: EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), et al.
Published: (2022-03-01)