Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes
Abstract Resistant cultivars are of value for protecting crops from disease, but can be rapidly overcome by pathogens. Several strategies have been proposed to delay pathogen adaptation (evolutionary control), while maintaining effective protection (epidemiological control). Resistance genes can be...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Evolutionary Applications |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/eva.13627 |
| _version_ | 1827365351673823232 |
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| author | Marta Zaffaroni Loup Rimbaud Jean‐François Rey Julien Papaïx Frédéric Fabre |
| author_facet | Marta Zaffaroni Loup Rimbaud Jean‐François Rey Julien Papaïx Frédéric Fabre |
| author_sort | Marta Zaffaroni |
| collection | DOAJ |
| description | Abstract Resistant cultivars are of value for protecting crops from disease, but can be rapidly overcome by pathogens. Several strategies have been proposed to delay pathogen adaptation (evolutionary control), while maintaining effective protection (epidemiological control). Resistance genes can be (i) combined in the same cultivar (pyramiding), (ii) deployed in different cultivars sown in the same field (mixtures) or in different fields (mosaics), or (iii) alternated over time (rotations). The outcomes of these strategies have been investigated principally in pathogens displaying pure clonal reproduction, but many pathogens have at least one sexual event in their annual life cycles. Sexual reproduction may promote the emergence of superpathogens adapted to all the resistance genes deployed. Here, we improved the spatially explicit stochastic model landsepi to include pathogen sexual reproduction, and we used the improved model to investigate the effect of sexual reproduction on evolutionary and epidemiological outcomes across deployment strategies for two major resistance genes. Sexual reproduction favours the establishment of a superpathogen when single mutant pathogens are present together at a sufficiently high frequency, as in mosaic and mixture strategies. However, sexual reproduction did not affect the strategy recommendations for a wide range of mutation probabilities, associated fitness costs, and landscape organisations. |
| first_indexed | 2024-03-08T08:28:03Z |
| format | Article |
| id | doaj.art-09f3a8ec712e4cc3a99ee2402049b944 |
| institution | Directory Open Access Journal |
| issn | 1752-4571 |
| language | English |
| last_indexed | 2024-03-08T08:28:03Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Evolutionary Applications |
| spelling | doaj.art-09f3a8ec712e4cc3a99ee2402049b9442024-02-02T04:15:45ZengWileyEvolutionary Applications1752-45712024-01-01171n/an/a10.1111/eva.13627Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapesMarta Zaffaroni0Loup Rimbaud1Jean‐François Rey2Julien Papaïx3Frédéric Fabre4INRAE, Bordeaux Sciences Agro, SAVE Villenave d'Ornon FranceINRAE, Pathologie Végétale Montfavet FranceINRAE, BioSP Avignon FranceINRAE, BioSP Avignon FranceINRAE, Bordeaux Sciences Agro, SAVE Villenave d'Ornon FranceAbstract Resistant cultivars are of value for protecting crops from disease, but can be rapidly overcome by pathogens. Several strategies have been proposed to delay pathogen adaptation (evolutionary control), while maintaining effective protection (epidemiological control). Resistance genes can be (i) combined in the same cultivar (pyramiding), (ii) deployed in different cultivars sown in the same field (mixtures) or in different fields (mosaics), or (iii) alternated over time (rotations). The outcomes of these strategies have been investigated principally in pathogens displaying pure clonal reproduction, but many pathogens have at least one sexual event in their annual life cycles. Sexual reproduction may promote the emergence of superpathogens adapted to all the resistance genes deployed. Here, we improved the spatially explicit stochastic model landsepi to include pathogen sexual reproduction, and we used the improved model to investigate the effect of sexual reproduction on evolutionary and epidemiological outcomes across deployment strategies for two major resistance genes. Sexual reproduction favours the establishment of a superpathogen when single mutant pathogens are present together at a sufficiently high frequency, as in mosaic and mixture strategies. However, sexual reproduction did not affect the strategy recommendations for a wide range of mutation probabilities, associated fitness costs, and landscape organisations.https://doi.org/10.1111/eva.13627deployment strategydisease controldurable resistanceevolutionary epidemiologysexual reproductionsimulation modelling |
| spellingShingle | Marta Zaffaroni Loup Rimbaud Jean‐François Rey Julien Papaïx Frédéric Fabre Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes Evolutionary Applications deployment strategy disease control durable resistance evolutionary epidemiology sexual reproduction simulation modelling |
| title | Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes |
| title_full | Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes |
| title_fullStr | Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes |
| title_full_unstemmed | Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes |
| title_short | Effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes |
| title_sort | effects of pathogen reproduction system on the evolutionary and epidemiological control provided by deployment strategies for two major resistance genes in agricultural landscapes |
| topic | deployment strategy disease control durable resistance evolutionary epidemiology sexual reproduction simulation modelling |
| url | https://doi.org/10.1111/eva.13627 |
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