FBXW24 controls female meiotic prophase progression by regulating SYCP3 ubiquitination

FBXW24 controls female meiotic prophase progression by regulating SYCP3 ubiquitination

Background An impeccable female meiotic prophase is critical for producing a high‐quality oocyte and, ultimately, a healthy newborn. SYCP3 is a key component of the synaptonemal complex regulating meiotic homologous recombination. However, what regulates SYCP3 stability is unknown. Methods Fertility...

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Bibliographic Details
Main Authors: Yang Wang, Wen‐Yi Gao, Li‐Li Wang, Ruo‐Lei Wang, Zhi‐Xia Yang, Fu‐Qiang Luo, Yu‐Hao He, Zi‐Bin Wang, Fu‐Qiang Wang, Qing‐Yuan Sun, Jing Li, Dong Zhang
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Clinical and Translational Medicine
Subjects:
FBXW24
meiotic prophase
oocyte
SYCP3
ubiquitination
Online Access:https://doi.org/10.1002/ctm2.891

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