Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysis

Introduction: Lead exposure is considered as a global health problem. The irreparable harmful effects of this heavy metal on human have been proven in various studies. Comparing to general population, workers in related industries are more exposed to lead. Several studies have investigated lead occu...

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Main Authors: Kourosh Sayehmiri, Marzieh Beigom Bigdeli Shamloo, Marzieh Khataee, Forghan Rabiei Fakhr, Milad Azami
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2016-09-01
Series:بهداشت و ایمنی کار
Subjects:
Online Access:http://jhsw.tums.ac.ir/browse.php?a_code=A-10-1-19&slc_lang=en&sid=1
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author Kourosh Sayehmiri
Marzieh Beigom Bigdeli Shamloo
Marzieh Khataee
Forghan Rabiei Fakhr
Milad Azami
author_facet Kourosh Sayehmiri
Marzieh Beigom Bigdeli Shamloo
Marzieh Khataee
Forghan Rabiei Fakhr
Milad Azami
author_sort Kourosh Sayehmiri
collection DOAJ
description Introduction: Lead exposure is considered as a global health problem. The irreparable harmful effects of this heavy metal on human have been proven in various studies. Comparing to general population, workers in related industries are more exposed to lead. Several studies have investigated lead occupational exposure and its biological evaluation in Iran; however there is no overall estimate. Thus, the present study was conducted to determine the occupational exposure to lead and its biological evaluation in Iranian workers, using systematic review and meta-analysis. Material and Method: This study was carried out based on information obtained from databases including Magiran, Iranmedex, SID, Medlib, Trials Register, Scopus, Pubmed, Science Direct, Cochran, Embase, Medline, Web of Science, Springer, Online Library Wiley, and Google Scholar from 1991 to 2016, using standard key words. All of the reviewed papers which met the inclusion criteria have been evaluated. Data combination was performed according to Random Effects Model using Stata software version 11.1. Result: In the 34 qualified studies, the mean blood lead level (BLL) concentration in Iranian workers was estimated 42.8µg/dl (95% CI: 35.15-50.49). The minimum and maximum BLL were belonged to west (28.348µg/dl) and center (45.928µg/dl) regions of Iran, respectively. Considering different occupations, the lowest mean value was reported in textile industry workers (12.3 µg/dl), while the highest value was for zinc-lead mine workers (72.6 µg/dl). Mean breathing air lead level of Iranian workers reported in 4 studies was estimated 0.23 mg/m3 (95% CI: 0.14-0.33). Conclusion: According to the high concentration of BLL and breathing air, it is recommended to increase protective measures and frequent screening. Scheduled clinical and paraclinical examination should also be performed for workers.
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spelling doaj.art-09f899ea3f434b5da561af781964c2682022-12-21T22:37:47ZfasTehran University of Medical Sciencesبهداشت و ایمنی کار2251-807X2383-20882016-09-0163114Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysisKourosh Sayehmiri0Marzieh Beigom Bigdeli Shamloo1Marzieh Khataee2Forghan Rabiei Fakhr3Milad Azami4 Associate Professor, Department of Biostatistics, Research Center for Prevention of Psychosocial Impairment, Ilam University of Medical Sciences , Ilam, Iran M.Sc., Nursing Education, Nursing and Midwifery School, Dezful University of Medical Sciences, Dezful, Iran Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran B.Sc of Lab Science, Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran Introduction: Lead exposure is considered as a global health problem. The irreparable harmful effects of this heavy metal on human have been proven in various studies. Comparing to general population, workers in related industries are more exposed to lead. Several studies have investigated lead occupational exposure and its biological evaluation in Iran; however there is no overall estimate. Thus, the present study was conducted to determine the occupational exposure to lead and its biological evaluation in Iranian workers, using systematic review and meta-analysis. Material and Method: This study was carried out based on information obtained from databases including Magiran, Iranmedex, SID, Medlib, Trials Register, Scopus, Pubmed, Science Direct, Cochran, Embase, Medline, Web of Science, Springer, Online Library Wiley, and Google Scholar from 1991 to 2016, using standard key words. All of the reviewed papers which met the inclusion criteria have been evaluated. Data combination was performed according to Random Effects Model using Stata software version 11.1. Result: In the 34 qualified studies, the mean blood lead level (BLL) concentration in Iranian workers was estimated 42.8µg/dl (95% CI: 35.15-50.49). The minimum and maximum BLL were belonged to west (28.348µg/dl) and center (45.928µg/dl) regions of Iran, respectively. Considering different occupations, the lowest mean value was reported in textile industry workers (12.3 µg/dl), while the highest value was for zinc-lead mine workers (72.6 µg/dl). Mean breathing air lead level of Iranian workers reported in 4 studies was estimated 0.23 mg/m3 (95% CI: 0.14-0.33). Conclusion: According to the high concentration of BLL and breathing air, it is recommended to increase protective measures and frequent screening. Scheduled clinical and paraclinical examination should also be performed for workers.http://jhsw.tums.ac.ir/browse.php?a_code=A-10-1-19&slc_lang=en&sid=1Biological Evaluation Iran Lead Meta-Analysis Occupational Exposure Systematic Review Workers
spellingShingle Kourosh Sayehmiri
Marzieh Beigom Bigdeli Shamloo
Marzieh Khataee
Forghan Rabiei Fakhr
Milad Azami
Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysis
بهداشت و ایمنی کار
Biological Evaluation
Iran
Lead
Meta-Analysis
Occupational Exposure
Systematic Review
Workers
title Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysis
title_full Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysis
title_fullStr Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysis
title_full_unstemmed Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysis
title_short Occupational exposure and biological evaluation of lead in Iranian workers-a systematic review and meta-analysis
title_sort occupational exposure and biological evaluation of lead in iranian workers a systematic review and meta analysis
topic Biological Evaluation
Iran
Lead
Meta-Analysis
Occupational Exposure
Systematic Review
Workers
url http://jhsw.tums.ac.ir/browse.php?a_code=A-10-1-19&slc_lang=en&sid=1
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AT marziehkhataee occupationalexposureandbiologicalevaluationofleadiniranianworkersasystematicreviewandmetaanalysis
AT forghanrabieifakhr occupationalexposureandbiologicalevaluationofleadiniranianworkersasystematicreviewandmetaanalysis
AT miladazami occupationalexposureandbiologicalevaluationofleadiniranianworkersasystematicreviewandmetaanalysis