Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis
Calciphylaxis is a rare and deadly vascular disease with poorly understood pathophysiology and without definitive treatment. Early presentations include skin ulcers with risk factors including end stage renal disease on hemodialysis, hypertension, hyperlipidemia, and diabetes mellitus. In our case,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323000511 |
| _version_ | 1797894913600258048 |
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| author | Jawad Shabani, MD Vaibhav Shah, DO Vikash Jaiswal, MD Akanksha Sharma, MD David Song, DO |
| author_facet | Jawad Shabani, MD Vaibhav Shah, DO Vikash Jaiswal, MD Akanksha Sharma, MD David Song, DO |
| author_sort | Jawad Shabani, MD |
| collection | DOAJ |
| description | Calciphylaxis is a rare and deadly vascular disease with poorly understood pathophysiology and without definitive treatment. Early presentations include skin ulcers with risk factors including end stage renal disease on hemodialysis, hypertension, hyperlipidemia, and diabetes mellitus. In our case, we present an 80-year-old female with multiple risk factors including hemodialysis and clinical features of necrotic and gangrenous skin lesions diagnostic of calciphylaxis who became hemodynamically unstable and ultimately expired secondary to toxic sequelae. We illustrate this case to explore early clinical presentation, limitations of current disease management and treatments, and the role for further studies to improve diagnosis and reduce mortality. |
| first_indexed | 2024-04-10T07:16:56Z |
| format | Article |
| id | doaj.art-09fc0a5288ae4d0faf75f3ae459d6e16 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-10T07:16:56Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-09fc0a5288ae4d0faf75f3ae459d6e162023-02-25T04:09:46ZengElsevierRadiology Case Reports1930-04332023-04-0118415221526Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxisJawad Shabani, MD0Vaibhav Shah, DO1Vikash Jaiswal, MD2Akanksha Sharma, MD3David Song, DO4Department of Internal Medicine, Icahn School of Medicine at Mount Sinai Elmhurst Hospital Center, Queens, NY, USADepartment of Internal Medicine, Icahn School of Medicine at Mount Sinai Elmhurst Hospital Center, Queens, NY, USALarkin Community Hospital, South Miami, FL, 33143, USA; Corresponding author at: Larkin Community Hospital, South Miami, FL, 33143, USA.Department of Internal Medicine, UPMC Mercy, Pittsburg, PA, USADepartment of Internal Medicine, Icahn School of Medicine at Mount Sinai Elmhurst Hospital Center, Queens, NY, USACalciphylaxis is a rare and deadly vascular disease with poorly understood pathophysiology and without definitive treatment. Early presentations include skin ulcers with risk factors including end stage renal disease on hemodialysis, hypertension, hyperlipidemia, and diabetes mellitus. In our case, we present an 80-year-old female with multiple risk factors including hemodialysis and clinical features of necrotic and gangrenous skin lesions diagnostic of calciphylaxis who became hemodynamically unstable and ultimately expired secondary to toxic sequelae. We illustrate this case to explore early clinical presentation, limitations of current disease management and treatments, and the role for further studies to improve diagnosis and reduce mortality.http://www.sciencedirect.com/science/article/pii/S1930043323000511CalciphylaxisHemodialysisSkin ulcersVasculopathy |
| spellingShingle | Jawad Shabani, MD Vaibhav Shah, DO Vikash Jaiswal, MD Akanksha Sharma, MD David Song, DO Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis Radiology Case Reports Calciphylaxis Hemodialysis Skin ulcers Vasculopathy |
| title | Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis |
| title_full | Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis |
| title_fullStr | Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis |
| title_full_unstemmed | Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis |
| title_short | Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis |
| title_sort | chronic skin ulcers in hemodialysis patient a fatal case of calciphylaxis |
| topic | Calciphylaxis Hemodialysis Skin ulcers Vasculopathy |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323000511 |
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