False pharmacoresistance – a true problem
Pharmacoresistant epilepsy poses a great burden to patients, their families, and the whole healthcare system, with numerous social, economic, physical, and psychical consequences. Hence, it is a diagnosis that has to be made only in cases of high certainty, after all potential causes of epilepsy...
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Format: | Article |
Language: | English |
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Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2021-01-01
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Series: | Acta Clinica Croatica |
Subjects: | |
Online Access: | https://hrcak.srce.hr/file/407495 |
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author | Silvio Bašić Ivana Marković Davor Sporiš Ivana Šušak Sporiš Filip Đerke Ivana Mrđen |
author_facet | Silvio Bašić Ivana Marković Davor Sporiš Ivana Šušak Sporiš Filip Đerke Ivana Mrđen |
author_sort | Silvio Bašić |
collection | DOAJ |
description | Pharmacoresistant epilepsy poses a great burden to patients, their families, and the
whole healthcare system, with numerous social, economic, physical, and psychical consequences.
Hence, it is a diagnosis that has to be made only in cases of high certainty, after all potential causes of
epilepsy have been evaluated. One of the important causes of pharmacoresistant epilepsy is false pharmacoresistance,
an entity that implies a condition in which poor disease control is not a consequence
of the biology of the disease itself, antiepileptic drug inefficacy, and/or patient specificity. It is a consequence
of human error and strongly depends on the experience of the treating physician, as well as on
the attitude of the patient. Despite its ‘falseness’, this entity is accompanied by real consequences for
the patient and his family, and at the same time, it delays appropriate treatment of the actual disease
from which the patient is suffering. In order to introduce appropriate treatment and avoid unnecessary
and harmful diagnostic procedures, false pharmacoresistance is a condition that has to be ruled out in
any patient with difficult-to-treat seizures. |
first_indexed | 2024-04-24T09:10:05Z |
format | Article |
id | doaj.art-09fc58560d1e48008dd1be394e89c684 |
institution | Directory Open Access Journal |
issn | 0353-9466 1333-9451 |
language | English |
last_indexed | 2024-04-24T09:10:05Z |
publishDate | 2021-01-01 |
publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
record_format | Article |
series | Acta Clinica Croatica |
spelling | doaj.art-09fc58560d1e48008dd1be394e89c6842024-04-15T17:54:12ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512021-01-0160.Supplement 391510.20471/acc.2021.60.s3.01False pharmacoresistance – a true problemSilvio Bašić0Ivana Marković1Davor Sporiš2Ivana Šušak Sporiš3Filip Đerke4Ivana Mrđen5Department of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, CroatiaDepartment of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, CroatiaDepartment of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, CroatiaDepartment of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, CroatiaDepartment of Neurology, Dubrava University Hospital, Zagreb, Croatia; Department of Psychiatry and Neurology, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University, Osijek, CroatiaDepartment of Neurology, Zadar General Hospital, Zadar, CroatiaPharmacoresistant epilepsy poses a great burden to patients, their families, and the whole healthcare system, with numerous social, economic, physical, and psychical consequences. Hence, it is a diagnosis that has to be made only in cases of high certainty, after all potential causes of epilepsy have been evaluated. One of the important causes of pharmacoresistant epilepsy is false pharmacoresistance, an entity that implies a condition in which poor disease control is not a consequence of the biology of the disease itself, antiepileptic drug inefficacy, and/or patient specificity. It is a consequence of human error and strongly depends on the experience of the treating physician, as well as on the attitude of the patient. Despite its ‘falseness’, this entity is accompanied by real consequences for the patient and his family, and at the same time, it delays appropriate treatment of the actual disease from which the patient is suffering. In order to introduce appropriate treatment and avoid unnecessary and harmful diagnostic procedures, false pharmacoresistance is a condition that has to be ruled out in any patient with difficult-to-treat seizures.https://hrcak.srce.hr/file/407495EpilepsyFalse pharmacoresistanceAntiepileptic drugsPharmacoresistant epilepsy |
spellingShingle | Silvio Bašić Ivana Marković Davor Sporiš Ivana Šušak Sporiš Filip Đerke Ivana Mrđen False pharmacoresistance – a true problem Acta Clinica Croatica Epilepsy False pharmacoresistance Antiepileptic drugs Pharmacoresistant epilepsy |
title | False pharmacoresistance – a true problem |
title_full | False pharmacoresistance – a true problem |
title_fullStr | False pharmacoresistance – a true problem |
title_full_unstemmed | False pharmacoresistance – a true problem |
title_short | False pharmacoresistance – a true problem |
title_sort | false pharmacoresistance a true problem |
topic | Epilepsy False pharmacoresistance Antiepileptic drugs Pharmacoresistant epilepsy |
url | https://hrcak.srce.hr/file/407495 |
work_keys_str_mv | AT silviobasic falsepharmacoresistanceatrueproblem AT ivanamarkovic falsepharmacoresistanceatrueproblem AT davorsporis falsepharmacoresistanceatrueproblem AT ivanasusaksporis falsepharmacoresistanceatrueproblem AT filipđerke falsepharmacoresistanceatrueproblem AT ivanamrđen falsepharmacoresistanceatrueproblem |