Molecular Regulation of Histamine Synthesis

Molecular Regulation of Histamine Synthesis

Histamine is a critical mediator of IgE/mast cell-mediated anaphylaxis, a neurotransmitter and a regulator of gastric acid secretion. Histamine is a monoamine synthesized from the amino acid histidine through a reaction catalyzed by the enzyme histidine decarboxylase (HDC), which removes carboxyl gr...

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Bibliographic Details
Main Authors: Hua Huang, Yapeng Li, Jinyi Liang, Fred D. Finkelman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
histamine
histidine decarboxylase
enhancers
promoter
gene regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01392/full

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