Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study
COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines has been one of the factors leading to hesita...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-01-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2023.2191576 |
| _version_ | 1827806312905310208 |
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| author | Monica Mtei Innocent B. Mboya Melina Mgongo Rachel Manongi Caroline Amour Julieth S. Bilakwate Ahmed Y. Nyaki James Ngocho Norman Jonas Amina Farah Maryam Amour Albino Kalolo James T. Kengia Florian Tinuga Frida Ngalesoni Abdalla H. Bakari Fatimata B. Kirakoya Awet Araya Ntuli A. Kapologwe Sia E. Msuya |
| author_facet | Monica Mtei Innocent B. Mboya Melina Mgongo Rachel Manongi Caroline Amour Julieth S. Bilakwate Ahmed Y. Nyaki James Ngocho Norman Jonas Amina Farah Maryam Amour Albino Kalolo James T. Kengia Florian Tinuga Frida Ngalesoni Abdalla H. Bakari Fatimata B. Kirakoya Awet Araya Ntuli A. Kapologwe Sia E. Msuya |
| author_sort | Monica Mtei |
| collection | DOAJ |
| description | COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines has been one of the factors leading to hesitancy. We aimed to assess the COVID-19 vaccine confidence (safety and effectiveness), associated factors, and its effects on vaccine uptake among general community members in Tanzania. This was a community-based cross-sectional survey conducted from December 2021 to April 2022 in six regions of Tanzania mainland and two regions in Zanzibar. Participants were interviewed using an electronic questionnaire. Multiple logistic regression models estimated odds ratios (ORs) and 95% confidence interval (CI) for factors associated with vaccine confidence. All analyses were performed using SPSS version 25.0. The study enrolled 3470 general Tanzanian community members; their mean age was 40.3 (standard deviation ±14.9) years, and 34% were males. The proportion of COVID-19 vaccine confidence was 54.6%. Geographical region, residence area, COVID-19 disease risk perception, and good knowledge of COVID-19 vaccines were significantly associated with COVID-19 vaccine confidence. Confidence in COVID-19 vaccines was associated with over three times higher odds of vaccine uptake. Confidence in COVID-19 vaccines was low in Tanzania. Innovative community engagement strategies and region-specific interventions are needed to improve comprehensive knowledge and address community perceptions and attitudes toward COVID-19 vaccines. |
| first_indexed | 2024-03-11T21:39:24Z |
| format | Article |
| id | doaj.art-0a02d5ae2b4d4979ab2aa92eb9f5b5dd |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:39:24Z |
| publishDate | 2023-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-0a02d5ae2b4d4979ab2aa92eb9f5b5dd2023-09-26T13:25:49ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-01-0119110.1080/21645515.2023.21915762191576Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional studyMonica Mtei0Innocent B. Mboya1Melina Mgongo2Rachel Manongi3Caroline Amour4Julieth S. Bilakwate5Ahmed Y. Nyaki6James Ngocho7Norman Jonas8Amina Farah9Maryam Amour10Albino Kalolo11James T. Kengia12Florian Tinuga13Frida Ngalesoni14Abdalla H. Bakari15Fatimata B. Kirakoya16Awet Araya17Ntuli A. Kapologwe18Sia E. Msuya19Kilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical University CollegeKilimanjaro Christian Medical CentreMuhimbili University of Health and Allied SciencesSt. Francis University College of Health and Allied SciencesPresident’s Office - Regional Administration and Local GovernmentImmunization and Vaccine Development DepartmentAfrican Medical and Research FoundationThe State University of ZanzibarUNICEF, Tanzania OfficeUNICEF, Tanzania OfficePresident’s Office - Regional Administration and Local GovernmentKilimanjaro Christian Medical University CollegeCOVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines has been one of the factors leading to hesitancy. We aimed to assess the COVID-19 vaccine confidence (safety and effectiveness), associated factors, and its effects on vaccine uptake among general community members in Tanzania. This was a community-based cross-sectional survey conducted from December 2021 to April 2022 in six regions of Tanzania mainland and two regions in Zanzibar. Participants were interviewed using an electronic questionnaire. Multiple logistic regression models estimated odds ratios (ORs) and 95% confidence interval (CI) for factors associated with vaccine confidence. All analyses were performed using SPSS version 25.0. The study enrolled 3470 general Tanzanian community members; their mean age was 40.3 (standard deviation ±14.9) years, and 34% were males. The proportion of COVID-19 vaccine confidence was 54.6%. Geographical region, residence area, COVID-19 disease risk perception, and good knowledge of COVID-19 vaccines were significantly associated with COVID-19 vaccine confidence. Confidence in COVID-19 vaccines was associated with over three times higher odds of vaccine uptake. Confidence in COVID-19 vaccines was low in Tanzania. Innovative community engagement strategies and region-specific interventions are needed to improve comprehensive knowledge and address community perceptions and attitudes toward COVID-19 vaccines.http://dx.doi.org/10.1080/21645515.2023.2191576covid-19covid-19 vaccinevaccine confidencevaccine hesitancyvaccine acceptancetanzania |
| spellingShingle | Monica Mtei Innocent B. Mboya Melina Mgongo Rachel Manongi Caroline Amour Julieth S. Bilakwate Ahmed Y. Nyaki James Ngocho Norman Jonas Amina Farah Maryam Amour Albino Kalolo James T. Kengia Florian Tinuga Frida Ngalesoni Abdalla H. Bakari Fatimata B. Kirakoya Awet Araya Ntuli A. Kapologwe Sia E. Msuya Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study Human Vaccines & Immunotherapeutics covid-19 covid-19 vaccine vaccine confidence vaccine hesitancy vaccine acceptance tanzania |
| title | Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study |
| title_full | Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study |
| title_fullStr | Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study |
| title_full_unstemmed | Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study |
| title_short | Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania: A community-based cross-sectional study |
| title_sort | confidence in covid 19 vaccine effectiveness and safety and its effect on vaccine uptake in tanzania a community based cross sectional study |
| topic | covid-19 covid-19 vaccine vaccine confidence vaccine hesitancy vaccine acceptance tanzania |
| url | http://dx.doi.org/10.1080/21645515.2023.2191576 |
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