Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.

The scope of ocular fluorometry is to monitor exogenous and endogenous fluorophores in ocular tissues, in relation with ophthalmic and systemic diseases using the unique optical prospectives of the eye. The elderly population and the incidence of blindness are increasing rapidly due to more cases of...

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Main Authors: E B Leite, J G Cunha-Vaz
Format: Article
Language:English
Published: Ordem dos Médicos 1992-01-01
Series:Acta Médica Portuguesa
Online Access:https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3189
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author E B Leite
J G Cunha-Vaz
author_facet E B Leite
J G Cunha-Vaz
author_sort E B Leite
collection DOAJ
description The scope of ocular fluorometry is to monitor exogenous and endogenous fluorophores in ocular tissues, in relation with ophthalmic and systemic diseases using the unique optical prospectives of the eye. The elderly population and the incidence of blindness are increasing rapidly due to more cases of diabetes, glaucoma, cataract and age-related macular degeneration. Monitoring changes in specific fluorophores in the eye may help identify the high risk groups in these diseases. New developments in instrumentation include differential fluorometry and introduction of confocal optics. Differential fluorometry has already achieved significant progress for the study of the autofluorescence of the lens and cornea and measurements in the aqueous. Improved spatial resolution obtained with improved optics opens interesting possibilities like measurement of corneal endothelial permeability and retinal vascular permeability. The results already obtained will be presented with particular incidence on measurements of lens fluorescence (normals--336.2 +/- 56.3; diabetes--659.9 +/- 123.9; age group--40-50 y) and corneal endothelial permeability (normals--3.14 +/- 60.10(-1) cm-1).
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spelling doaj.art-0a0914ded173483eb8ba3d0d409e689c2022-12-22T03:30:29ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07581992-01-015110.20344/amp.3189Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.E B Leite0J G Cunha-VazCentro de Oftalmologia, Universidade de Coimbra, Hospitais da Universidade de Coimbra, Portugal.The scope of ocular fluorometry is to monitor exogenous and endogenous fluorophores in ocular tissues, in relation with ophthalmic and systemic diseases using the unique optical prospectives of the eye. The elderly population and the incidence of blindness are increasing rapidly due to more cases of diabetes, glaucoma, cataract and age-related macular degeneration. Monitoring changes in specific fluorophores in the eye may help identify the high risk groups in these diseases. New developments in instrumentation include differential fluorometry and introduction of confocal optics. Differential fluorometry has already achieved significant progress for the study of the autofluorescence of the lens and cornea and measurements in the aqueous. Improved spatial resolution obtained with improved optics opens interesting possibilities like measurement of corneal endothelial permeability and retinal vascular permeability. The results already obtained will be presented with particular incidence on measurements of lens fluorescence (normals--336.2 +/- 56.3; diabetes--659.9 +/- 123.9; age group--40-50 y) and corneal endothelial permeability (normals--3.14 +/- 60.10(-1) cm-1).https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3189
spellingShingle E B Leite
J G Cunha-Vaz
Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.
Acta Médica Portuguesa
title Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.
title_full Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.
title_fullStr Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.
title_full_unstemmed Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.
title_short Futuros desenvolvimentos na instrumentação em fluorofotometria ocular.
title_sort futuros desenvolvimentos na instrumentacao em fluorofotometria ocular
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3189
work_keys_str_mv AT ebleite futurosdesenvolvimentosnainstrumentacaoemfluorofotometriaocular
AT jgcunhavaz futurosdesenvolvimentosnainstrumentacaoemfluorofotometriaocular