EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODEL
Ocimum selloi is a plant used in traditional medicine as a tea; however, no studies have reported the biological activity of the aqueous extract of this plant. This study aimed to evaluate the cytotoxicity, genotoxicity, and mutagenicity of two concentrations of an aqueous extract prepared by infusi...
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| Format: | Article |
| Language: | English |
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Universidade Estadual de Mato Grosso do Sul
2021-02-01
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| Series: | Revista de Agricultura Neotropical |
| Online Access: | https://periodicosonline.uems.br/index.php/agrineo/article/view/5647 |
| _version_ | 1818925496037015552 |
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| author | Maria do Socorro Mascarenhas Santos Maria Helena Verdan Raul Cremonezi Piva Lucilene Finoto Viana Claudia Andrea Lima Cardoso |
| author_facet | Maria do Socorro Mascarenhas Santos Maria Helena Verdan Raul Cremonezi Piva Lucilene Finoto Viana Claudia Andrea Lima Cardoso |
| author_sort | Maria do Socorro Mascarenhas Santos |
| collection | DOAJ |
| description | Ocimum selloi is a plant used in traditional medicine as a tea; however, no studies have reported the biological activity of the aqueous extract of this plant. This study aimed to evaluate the cytotoxicity, genotoxicity, and mutagenicity of two concentrations of an aqueous extract prepared by infusion of leaves from O. selloi using the Allium cepa model. The O. selloi infusion contained 107.1 ± 1.27 mg GAE g-1. In the A. cepa test, the concentration of the extract influenced the germination index; for 1.0 mg mL-1, it was 60.78% and for 5.0 mg mL-1, it was 51.14%. The evaluation of root development also showed differences between the two concentrations and the negative control, and differences in mitotic index were observed between the concentrations and the negative control; the concentration of 1.0 mg mL-1 showed an index of 4.1%, and for 5.0 mg mL-1 it was 3.7%. An index of chromosomal changes of 0.1% was observed for a concentration of 5.0 mg mL-1. The A. cepa test therefore showed that the studied concentrations did not cause deformations in cells, cell death or mutagenic alterations. |
| first_indexed | 2024-12-20T02:42:09Z |
| format | Article |
| id | doaj.art-0a0fabc97cc64fdab3810141347cdc5d |
| institution | Directory Open Access Journal |
| issn | 2358-6303 |
| language | English |
| last_indexed | 2024-12-20T02:42:09Z |
| publishDate | 2021-02-01 |
| publisher | Universidade Estadual de Mato Grosso do Sul |
| record_format | Article |
| series | Revista de Agricultura Neotropical |
| spelling | doaj.art-0a0fabc97cc64fdab3810141347cdc5d2022-12-21T19:56:17ZengUniversidade Estadual de Mato Grosso do SulRevista de Agricultura Neotropical2358-63032021-02-0181e5647e564710.32404/rean.v8i1.56473441EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODELMaria do Socorro Mascarenhas Santos0Maria Helena Verdan1Raul Cremonezi Piva2Lucilene Finoto Viana3Claudia Andrea Lima Cardoso4Universidade Estadual de mato Grosso do Sul/UEMS Programa de Pós-Graduação em Recursos Naturais /PGRN, Dourados.Universidade Federal da Grande Dourados/UFGD.Universidade Federal da Grande Dourados/UFGD.Universidade Federal da Grande Dourados/UFGD.Universidade Estadual de Mato Grosso do Sul/UEMS, Dourados.Ocimum selloi is a plant used in traditional medicine as a tea; however, no studies have reported the biological activity of the aqueous extract of this plant. This study aimed to evaluate the cytotoxicity, genotoxicity, and mutagenicity of two concentrations of an aqueous extract prepared by infusion of leaves from O. selloi using the Allium cepa model. The O. selloi infusion contained 107.1 ± 1.27 mg GAE g-1. In the A. cepa test, the concentration of the extract influenced the germination index; for 1.0 mg mL-1, it was 60.78% and for 5.0 mg mL-1, it was 51.14%. The evaluation of root development also showed differences between the two concentrations and the negative control, and differences in mitotic index were observed between the concentrations and the negative control; the concentration of 1.0 mg mL-1 showed an index of 4.1%, and for 5.0 mg mL-1 it was 3.7%. An index of chromosomal changes of 0.1% was observed for a concentration of 5.0 mg mL-1. The A. cepa test therefore showed that the studied concentrations did not cause deformations in cells, cell death or mutagenic alterations.https://periodicosonline.uems.br/index.php/agrineo/article/view/5647 |
| spellingShingle | Maria do Socorro Mascarenhas Santos Maria Helena Verdan Raul Cremonezi Piva Lucilene Finoto Viana Claudia Andrea Lima Cardoso EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODEL Revista de Agricultura Neotropical |
| title | EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODEL |
| title_full | EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODEL |
| title_fullStr | EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODEL |
| title_full_unstemmed | EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODEL |
| title_short | EVALUATION OF THE EFFECTS OF THE INFUSION OF Ocimum selloi LEAVES USING THE Allium cepa MODEL |
| title_sort | evaluation of the effects of the infusion of ocimum selloi leaves using the allium cepa model |
| url | https://periodicosonline.uems.br/index.php/agrineo/article/view/5647 |
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