Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients
Objective:Percutaneous coronary intervention (PCI) has become the treatment method for patients presenting with ST elevation myocardial infarction (STEMI). One of the well-known complications of PCI is no-reflow. Studies demonstrated a relationship between endothelial dysfunction and disturbed vascu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-12-01
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| Series: | Bagcilar Medical Bulletin |
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http://behmedicalbulletin.org/archives/archive-detail/article-preview/association-between-bifurcation-angle-and-coronary/49057
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| _version_ | 1828029751938252800 |
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| author | Ömer Taşbulak Mustafa Duran Ahmet Anıl Şahin Ali Rıza Demir Recep Gülmez Mehmet Ertürk Mehmet Emin Kalkan |
| author_facet | Ömer Taşbulak Mustafa Duran Ahmet Anıl Şahin Ali Rıza Demir Recep Gülmez Mehmet Ertürk Mehmet Emin Kalkan |
| author_sort | Ömer Taşbulak |
| collection | DOAJ |
| description | Objective:Percutaneous coronary intervention (PCI) has become the treatment method for patients presenting with ST elevation myocardial infarction (STEMI). One of the well-known complications of PCI is no-reflow. Studies demonstrated a relationship between endothelial dysfunction and disturbed vascular flow due to angulation of vascular tree. Although the relationship between hemodynamic alterations and coronary angulation is evident, there is a lack of detailed analysis in terms of hemodynamic changes between vascular geometry and coronary no-reflow. We aimed to elucidate the relationship between vascular geometry and coronary no-reflow.Method:We reviewed PCI database of our hospital and enrolled a total of 120 patients with STEMI, who developed no-reflow following PCI, and sex and age matched 80 patients with normal flow. For each group, demographic and clinical characteristics, laboratory values and two dimensional quantitative coronary angiography measurements were evaluated.Results:Patients with no-reflow had a higher prevalence of hypertension and diabetes mellitus. In addition, serum C-reactive protein levels were higher in patients with no-reflow compared to patients with normal flow (p<0.001). On the other hand, serum hemoglobin levels were significantly lower in patients with no-reflow compared to patients with normal flow (p<0.001). With respect to 3 dimensional coronary measurements, calculated bifurcation angle of left anterior descending artery (LAD) and circumflex artery (CX) was significantly wider in the no-reflow group than in the control group [110.9° (21.8°) vs. 85.9° (15.8°), p<0.001].Conclusion:Our data showed that a strong association existed between bifurcation angle of LAD-CX and no-reflow phenomenon in STEMI patients who underwent PCI. |
| first_indexed | 2024-04-10T14:16:02Z |
| format | Article |
| id | doaj.art-0a12a6dfd78442a9b47493ff41c5b1c7 |
| institution | Directory Open Access Journal |
| issn | 2547-9431 |
| language | English |
| last_indexed | 2024-04-10T14:16:02Z |
| publishDate | 2021-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Bagcilar Medical Bulletin |
| spelling | doaj.art-0a12a6dfd78442a9b47493ff41c5b1c72023-02-15T16:09:32ZengGalenos YayineviBagcilar Medical Bulletin2547-94312021-12-016436136910.4274/BMB.galenos.2021.04.04413049054Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in PatientsÖmer Taşbulak0Mustafa Duran1Ahmet Anıl Şahin2Ali Rıza Demir3Recep Gülmez4Mehmet Ertürk5Mehmet Emin Kalkan6 University of Health Sciences Turkey, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Clinic of Cardiology, İstanbul, Turkey Konya Training and Research Hospital, Clinic of Cardiology, Konya, Turkey İstinye University, Liv Bahçeşehir Hospital, Clinic of Cardiology, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Clinic of Cardiology, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Clinic of Cardiology, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Clinic of Cardiology, İstanbul, Turkey University of Health Sciences Turkey, Başahşehir Çam ve Sakura City Hospital, Clinic of Cardiology, İstanbul, Turkey Objective:Percutaneous coronary intervention (PCI) has become the treatment method for patients presenting with ST elevation myocardial infarction (STEMI). One of the well-known complications of PCI is no-reflow. Studies demonstrated a relationship between endothelial dysfunction and disturbed vascular flow due to angulation of vascular tree. Although the relationship between hemodynamic alterations and coronary angulation is evident, there is a lack of detailed analysis in terms of hemodynamic changes between vascular geometry and coronary no-reflow. We aimed to elucidate the relationship between vascular geometry and coronary no-reflow.Method:We reviewed PCI database of our hospital and enrolled a total of 120 patients with STEMI, who developed no-reflow following PCI, and sex and age matched 80 patients with normal flow. For each group, demographic and clinical characteristics, laboratory values and two dimensional quantitative coronary angiography measurements were evaluated.Results:Patients with no-reflow had a higher prevalence of hypertension and diabetes mellitus. In addition, serum C-reactive protein levels were higher in patients with no-reflow compared to patients with normal flow (p<0.001). On the other hand, serum hemoglobin levels were significantly lower in patients with no-reflow compared to patients with normal flow (p<0.001). With respect to 3 dimensional coronary measurements, calculated bifurcation angle of left anterior descending artery (LAD) and circumflex artery (CX) was significantly wider in the no-reflow group than in the control group [110.9° (21.8°) vs. 85.9° (15.8°), p<0.001].Conclusion:Our data showed that a strong association existed between bifurcation angle of LAD-CX and no-reflow phenomenon in STEMI patients who underwent PCI. http://behmedicalbulletin.org/archives/archive-detail/article-preview/association-between-bifurcation-angle-and-coronary/49057 bifurcation angleno reflowpercutaneous coronary intervention |
| spellingShingle | Ömer Taşbulak Mustafa Duran Ahmet Anıl Şahin Ali Rıza Demir Recep Gülmez Mehmet Ertürk Mehmet Emin Kalkan Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients Bagcilar Medical Bulletin bifurcation angle no reflow percutaneous coronary intervention |
| title | Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients |
| title_full | Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients |
| title_fullStr | Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients |
| title_full_unstemmed | Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients |
| title_short | Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients |
| title_sort | association between bifurcation angle and coronary no reflow following primary percutaneous coronary intervention in patients |
| topic | bifurcation angle no reflow percutaneous coronary intervention |
| url |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/association-between-bifurcation-angle-and-coronary/49057
|
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