Two Cases of Hepatoblastoma in Adults
Adult hepatoblastoma is a rare tumor whose etiology and mechanisms of development are still incompletely understood. Imaging and biological tests such as AFP and liver enzymes are non-specific. Histologically, there are 2 histological variants: pure epithelial with 5 types (pure fetal, embryonal, sm...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-10-01
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| Series: | Clinical Pathology |
| Online Access: | https://doi.org/10.1177/2632010X221129592 |
| _version_ | 1811198490024345600 |
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| author | Elouarith Ihssan Elagouri Hajar Bekarsabein Salma Ech-Charif Soumaya Mahdi Youssef Khmou Mouna El Khannoussi Basma |
| author_facet | Elouarith Ihssan Elagouri Hajar Bekarsabein Salma Ech-Charif Soumaya Mahdi Youssef Khmou Mouna El Khannoussi Basma |
| author_sort | Elouarith Ihssan |
| collection | DOAJ |
| description | Adult hepatoblastoma is a rare tumor whose etiology and mechanisms of development are still incompletely understood. Imaging and biological tests such as AFP and liver enzymes are non-specific. Histologically, there are 2 histological variants: pure epithelial with 5 types (pure fetal, embryonal, small cell undifferentiated, cholangioblastic, and macrotrabecular), a mixed epithelial and a mesenchymal variant with or without a teratoid contingent. The main differential diagnosis concerns hepatocellular carcinoma. The treatment of hepatoblastoma in adults is not yet standardized and surgery remains the mainstay of treatment. In this report we aim to describe the clinical, pathological, and immunohistochemical features of this rare entity in adult patients and discuss the elements allowing its distinction from hepatocellular carcinoma (HCC). |
| first_indexed | 2024-04-12T01:32:38Z |
| format | Article |
| id | doaj.art-0a130b588a5a47c99b7681c5cced61f5 |
| institution | Directory Open Access Journal |
| issn | 2632-010X |
| language | English |
| last_indexed | 2024-04-12T01:32:38Z |
| publishDate | 2022-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Pathology |
| spelling | doaj.art-0a130b588a5a47c99b7681c5cced61f52022-12-22T03:53:27ZengSAGE PublishingClinical Pathology2632-010X2022-10-011510.1177/2632010X221129592Two Cases of Hepatoblastoma in AdultsElouarith IhssanElagouri HajarBekarsabein SalmaEch-Charif SoumayaMahdi YoussefKhmou MounaEl Khannoussi BasmaAdult hepatoblastoma is a rare tumor whose etiology and mechanisms of development are still incompletely understood. Imaging and biological tests such as AFP and liver enzymes are non-specific. Histologically, there are 2 histological variants: pure epithelial with 5 types (pure fetal, embryonal, small cell undifferentiated, cholangioblastic, and macrotrabecular), a mixed epithelial and a mesenchymal variant with or without a teratoid contingent. The main differential diagnosis concerns hepatocellular carcinoma. The treatment of hepatoblastoma in adults is not yet standardized and surgery remains the mainstay of treatment. In this report we aim to describe the clinical, pathological, and immunohistochemical features of this rare entity in adult patients and discuss the elements allowing its distinction from hepatocellular carcinoma (HCC).https://doi.org/10.1177/2632010X221129592 |
| spellingShingle | Elouarith Ihssan Elagouri Hajar Bekarsabein Salma Ech-Charif Soumaya Mahdi Youssef Khmou Mouna El Khannoussi Basma Two Cases of Hepatoblastoma in Adults Clinical Pathology |
| title | Two Cases of Hepatoblastoma in Adults |
| title_full | Two Cases of Hepatoblastoma in Adults |
| title_fullStr | Two Cases of Hepatoblastoma in Adults |
| title_full_unstemmed | Two Cases of Hepatoblastoma in Adults |
| title_short | Two Cases of Hepatoblastoma in Adults |
| title_sort | two cases of hepatoblastoma in adults |
| url | https://doi.org/10.1177/2632010X221129592 |
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