The Activation of PDGFRβ on Mononuclear Stromal/Tumor Cells in Giant Cell Tumor of Bone After Denosumab Treatment. An Immunohistochemical Study of Five Cases

Due to the relatively high recurrence rate and the destructive nature of the tumor, the treatment of giant cell tumor is still a challenge. Denosumab appeared to be a promising candidate as a therapeutic drug. However, several studies have reported that tumors can recur during/after treatment with d...

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Bibliographic Details
Main Authors: Imre Antal, Zsuzsanna Pápai, Miklós Szendrői, Tamás Perlaky, Katalin Dezső, Zoltán Lippai, Zoltán Sápi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Pathology and Oncology Research
Subjects:
Online Access:https://www.por-journal.com/articles/10.3389/pore.2022.1610633/full