First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imaging
Target motion, particularly in the abdomen, due to respiration or patient movement is still a challenge in many diagnostic and therapeutic processes. Hence, methods to detect and compensate this motion are required. Diagnostic ultrasound represents a non-invasive and dose-free alternative to fluoros...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-11-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00258/full |
| _version_ | 1818244312487428096 |
|---|---|
| author | Julia eSchwaab Christopher eKurz Cristina eSarti André eBongers Frederic eSchoenahl Christoph eBert Jürgen eDebus Jürgen eDebus Katia eParodi Jürgen Walter Jenne Jürgen Walter Jenne |
| author_facet | Julia eSchwaab Christopher eKurz Cristina eSarti André eBongers Frederic eSchoenahl Christoph eBert Jürgen eDebus Jürgen eDebus Katia eParodi Jürgen Walter Jenne Jürgen Walter Jenne |
| author_sort | Julia eSchwaab |
| collection | DOAJ |
| description | Target motion, particularly in the abdomen, due to respiration or patient movement is still a challenge in many diagnostic and therapeutic processes. Hence, methods to detect and compensate this motion are required. Diagnostic ultrasound represents a non-invasive and dose-free alternative to fluoroscopy, providing more information about internal target motion than respiration belt or optical tracking.The goal of this project is to develop an ultrasound based motion tracking for real time motion correction in radiation therapy and diagnostic imaging, notably in 4D positron emission tomography (PET). In this work, a workflow is established to enable the transformation of ultrasound tracking data to the coordinates of the treatment delivery or imaging system – even if the ultrasound probe is moving due to respiration. It is shown that the ultrasound tracking signal is equally adequate for 4D PET image reconstruction as the clinically used respiration belt and provides additional opportunities in this concern. Furthermore, it is demonstrated that the ultrasound probe being within the PET field of view generally has no relevant influence on the image quality. The accuracy and precision of all the steps in the calibration workflow for ultrasound tracking based 4D PET imaging are found to be in an acceptable range for clinical implementation. Eventually, we show in vitro that an ultrasound based motion tracking in absolute room coordinates with a moving US-transducer is feasible. |
| first_indexed | 2024-12-12T14:15:01Z |
| format | Article |
| id | doaj.art-0a15d84f319a40c18580c446e492d154 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-12T14:15:01Z |
| publishDate | 2015-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-0a15d84f319a40c18580c446e492d1542022-12-22T00:21:56ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2015-11-01510.3389/fonc.2015.00258139569First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imagingJulia eSchwaab0Christopher eKurz1Cristina eSarti2André eBongers3Frederic eSchoenahl4Christoph eBert5Jürgen eDebus6Jürgen eDebus7Katia eParodi8Jürgen Walter Jenne9Jürgen Walter Jenne10mediri GmbHLudwig-Mayimilian-Universitymediri GmbHmediri GmbHSiemens Medical ImagingErlangen University HospitalHeidelberg Ion-Beam Therapy Center (HIT)Heidelberg University HospitalLudwig-Mayimilian-Universitymediri GmbHFraunhofer MEVISTarget motion, particularly in the abdomen, due to respiration or patient movement is still a challenge in many diagnostic and therapeutic processes. Hence, methods to detect and compensate this motion are required. Diagnostic ultrasound represents a non-invasive and dose-free alternative to fluoroscopy, providing more information about internal target motion than respiration belt or optical tracking.The goal of this project is to develop an ultrasound based motion tracking for real time motion correction in radiation therapy and diagnostic imaging, notably in 4D positron emission tomography (PET). In this work, a workflow is established to enable the transformation of ultrasound tracking data to the coordinates of the treatment delivery or imaging system – even if the ultrasound probe is moving due to respiration. It is shown that the ultrasound tracking signal is equally adequate for 4D PET image reconstruction as the clinically used respiration belt and provides additional opportunities in this concern. Furthermore, it is demonstrated that the ultrasound probe being within the PET field of view generally has no relevant influence on the image quality. The accuracy and precision of all the steps in the calibration workflow for ultrasound tracking based 4D PET imaging are found to be in an acceptable range for clinical implementation. Eventually, we show in vitro that an ultrasound based motion tracking in absolute room coordinates with a moving US-transducer is feasible.http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00258/fullultrasound imagingultrasound based motion detection4D PET imagingultrasound calibrationultrasound in PET/CT |
| spellingShingle | Julia eSchwaab Christopher eKurz Cristina eSarti André eBongers Frederic eSchoenahl Christoph eBert Jürgen eDebus Jürgen eDebus Katia eParodi Jürgen Walter Jenne Jürgen Walter Jenne First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imaging Frontiers in Oncology ultrasound imaging ultrasound based motion detection 4D PET imaging ultrasound calibration ultrasound in PET/CT |
| title | First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imaging |
| title_full | First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imaging |
| title_fullStr | First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imaging |
| title_full_unstemmed | First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imaging |
| title_short | First steps towards ultrasound-based motion compensation for imaging and therapy: calibration with an optical system and 4D PET imaging |
| title_sort | first steps towards ultrasound based motion compensation for imaging and therapy calibration with an optical system and 4d pet imaging |
| topic | ultrasound imaging ultrasound based motion detection 4D PET imaging ultrasound calibration ultrasound in PET/CT |
| url | http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00258/full |
| work_keys_str_mv | AT juliaeschwaab firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT christopherekurz firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT cristinaesarti firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT andreebongers firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT fredericeschoenahl firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT christophebert firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT jurgenedebus firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT jurgenedebus firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT katiaeparodi firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT jurgenwalterjenne firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging AT jurgenwalterjenne firststepstowardsultrasoundbasedmotioncompensationforimagingandtherapycalibrationwithanopticalsystemand4dpetimaging |