Transduction characteristics of alternative adeno-associated virus serotypes in the cat brain by intracisternal delivery
Multiple studies have examined the transduction characteristics of different AAV serotypes in the mouse brain, where they can exhibit significantly different patterns of transduction. The pattern of transduction also varies with the route of administration. Much less information exists for the trans...
Main Authors: | Jacqueline E. Hunter, Caitlyn M. Molony, Jessica H. Bagel, Patricia A. O’Donnell, Stephen G. Kaler, John H. Wolfe |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-09-01
|
Series: | Molecular Therapy: Methods & Clinical Development |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050122000997 |
Similar Items
-
Intracisternal delivery of NFkappaB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment.
by: Olivier eBockstael, et al.
Published: (2014-12-01) -
Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery
by: Sarah E. Sinnett, et al.
Published: (2017-06-01) -
Translational Feasibility of Lumbar Puncture for Intrathecal AAV Administration
by: Christian Hinderer, et al.
Published: (2020-06-01) -
Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability
by: Antonello Spinelli, et al.
Published: (2019-04-01) -
Pre-clinical delivery of gene therapy products to the cerebrospinal fluid: challenges and considerations for clinical translation
by: Ernesto A. Salegio, et al.
Published: (2023-08-01)