Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review
Introduction: The association between systemic sclerosis (SSc) and sexual dysfunction was controversial. Aim: To explore the impacts of SSc on sexual function, the prevalence of sexual dysfunction in patients with SSc and associated risk factors. Methods: A systematic review of all published studies...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press
2021-08-01
|
| Series: | Sexual Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2050116121000726 |
| _version_ | 1827835624536670208 |
|---|---|
| author | Rui Gao, MD Pingying Qing, MD, PhD Xiaochi Sun, MD Xun Zeng, MD, PhD Xiao Hu, MD Sirui Zhang, MD Yihong Yang, MD, PhD Lang Qin, MD, PhD |
| author_facet | Rui Gao, MD Pingying Qing, MD, PhD Xiaochi Sun, MD Xun Zeng, MD, PhD Xiao Hu, MD Sirui Zhang, MD Yihong Yang, MD, PhD Lang Qin, MD, PhD |
| author_sort | Rui Gao, MD |
| collection | DOAJ |
| description | Introduction: The association between systemic sclerosis (SSc) and sexual dysfunction was controversial. Aim: To explore the impacts of SSc on sexual function, the prevalence of sexual dysfunction in patients with SSc and associated risk factors. Methods: A systematic review of all published studies was performed. Studies exploring the association between SSc and sexual function were retrieved from PubMed, Web of Science, and EBSCO. All retrieved papers were selected according to the inclusion and exclusion criteria. Main Outcome Measure: The impacts of SSc on sexual function, the prevalence of sexual dysfunction in males and females with SSc and associated risk factors. Results: A total 12 studies were included in this study. The prevalence of sexual dysfunction in SSc males and SSc females were 76.9–81.4% and 46.7–86.6%, respectively. But the direct impacts of SSc on sexual function were controversial. EULAR SSc activity score ≥3, the number of complications ≥2, and the presence of anticardiolipin antibody and anti U1 ribonucleoprotein antibody in males and resistive index (RI) and the systolic/diastolic (S/D) ratio of clitoral blood in females have potential to be SSc-specific risk factors for sexual dysfunction. Clinical Implications: Clinicians need to pay more attention to the impacts of SSc on sexual function of patients especially in those with risk factors. Strengths & Limitations: Systematically explored the prevalence of sexual dysfunction in SSc males and females, and the risk factors of sexual dysfunction for SSc were explored innovatively. However, there were some limitations in included studies prevented exploring the impacts of SSc on sexual function deeply. Conclusion: Sexual dysfunction may be an important symptom of SSc, many risk factors may be associated with sexual dysfunction in males and females with SSc.Gao R, Qing P, Sun X, et al. Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review. Sex Med 2021;9:100392. |
| first_indexed | 2024-03-12T06:12:22Z |
| format | Article |
| id | doaj.art-0a183c8fc5264f41a1a2bd917204c4d7 |
| institution | Directory Open Access Journal |
| issn | 2050-1161 |
| language | English |
| last_indexed | 2024-03-12T06:12:22Z |
| publishDate | 2021-08-01 |
| publisher | Oxford University Press |
| record_format | Article |
| series | Sexual Medicine |
| spelling | doaj.art-0a183c8fc5264f41a1a2bd917204c4d72023-09-03T02:51:29ZengOxford University PressSexual Medicine2050-11612021-08-0194100392Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic ReviewRui Gao, MD0Pingying Qing, MD, PhD1Xiaochi Sun, MD2Xun Zeng, MD, PhD3Xiao Hu, MD4Sirui Zhang, MD5Yihong Yang, MD, PhD6Lang Qin, MD, PhD7The Reproductive Medical Center, Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China; West China School of Medicine, Sichuan University, Chengdu, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, ChinaDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, ChinaWest China School of Medicine, Sichuan University, Chengdu, ChinaThe Reproductive Medical Center, Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, ChinaWest China School of Medicine, Sichuan University, Chengdu, ChinaWest China School of Medicine, Sichuan University, Chengdu, ChinaThe Reproductive Medical Center, Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China; Corresponding Author: Yihong Yang, MD, PhD, No. 20, Section 3, South Renmin Road, Chengdu, Sichuan Province, China;The Reproductive Medical Center, Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China; Corresponding Author: Lang Qin, MD, PhD, No. 20, Section 3, South Renmin Road, Chengdu, Sichuan Province, China;Introduction: The association between systemic sclerosis (SSc) and sexual dysfunction was controversial. Aim: To explore the impacts of SSc on sexual function, the prevalence of sexual dysfunction in patients with SSc and associated risk factors. Methods: A systematic review of all published studies was performed. Studies exploring the association between SSc and sexual function were retrieved from PubMed, Web of Science, and EBSCO. All retrieved papers were selected according to the inclusion and exclusion criteria. Main Outcome Measure: The impacts of SSc on sexual function, the prevalence of sexual dysfunction in males and females with SSc and associated risk factors. Results: A total 12 studies were included in this study. The prevalence of sexual dysfunction in SSc males and SSc females were 76.9–81.4% and 46.7–86.6%, respectively. But the direct impacts of SSc on sexual function were controversial. EULAR SSc activity score ≥3, the number of complications ≥2, and the presence of anticardiolipin antibody and anti U1 ribonucleoprotein antibody in males and resistive index (RI) and the systolic/diastolic (S/D) ratio of clitoral blood in females have potential to be SSc-specific risk factors for sexual dysfunction. Clinical Implications: Clinicians need to pay more attention to the impacts of SSc on sexual function of patients especially in those with risk factors. Strengths & Limitations: Systematically explored the prevalence of sexual dysfunction in SSc males and females, and the risk factors of sexual dysfunction for SSc were explored innovatively. However, there were some limitations in included studies prevented exploring the impacts of SSc on sexual function deeply. Conclusion: Sexual dysfunction may be an important symptom of SSc, many risk factors may be associated with sexual dysfunction in males and females with SSc.Gao R, Qing P, Sun X, et al. Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review. Sex Med 2021;9:100392.http://www.sciencedirect.com/science/article/pii/S2050116121000726Systemic SclerosisSScSexual DysfunctionSystematic Review |
| spellingShingle | Rui Gao, MD Pingying Qing, MD, PhD Xiaochi Sun, MD Xun Zeng, MD, PhD Xiao Hu, MD Sirui Zhang, MD Yihong Yang, MD, PhD Lang Qin, MD, PhD Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review Sexual Medicine Systemic Sclerosis SSc Sexual Dysfunction Systematic Review |
| title | Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review |
| title_full | Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review |
| title_fullStr | Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review |
| title_full_unstemmed | Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review |
| title_short | Prevalence of Sexual Dysfunction in People With Systemic Sclerosis and the Associated Risk Factors: A Systematic Review |
| title_sort | prevalence of sexual dysfunction in people with systemic sclerosis and the associated risk factors a systematic review |
| topic | Systemic Sclerosis SSc Sexual Dysfunction Systematic Review |
| url | http://www.sciencedirect.com/science/article/pii/S2050116121000726 |
| work_keys_str_mv | AT ruigaomd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview AT pingyingqingmdphd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview AT xiaochisunmd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview AT xunzengmdphd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview AT xiaohumd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview AT siruizhangmd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview AT yihongyangmdphd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview AT langqinmdphd prevalenceofsexualdysfunctioninpeoplewithsystemicsclerosisandtheassociatedriskfactorsasystematicreview |