The Gut Microbiota Activates AhR Through the Tryptophan Metabolite Kyn to Mediate Renal Cell Carcinoma Metastasis

The Gut Microbiota Activates AhR Through the Tryptophan Metabolite Kyn to Mediate Renal Cell Carcinoma Metastasis

Background: The incidence of renal cell carcinoma (RCC) is increasing year by year. It is difficult to have complete treatment so far. Studies have shown that tryptophan metabolite Kynurenine (Kyn) affects cell proliferation, migration, apoptosis, adhesion, and differentiation. Our aim is to explore...

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Bibliographic Details
Main Authors: Guoyu Dai, Xiang Chen, Yao He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Nutrition
Subjects:
rcc
AhR
KYN
EMT
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.712327/full

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