Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules
This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules. The best dissolution in vitro profile was achieved using potassium phosphate buffer at pH 6.8 as the dissolution medium and paddle as the apparatus at 50 rpm....
Main Authors: | Taciane Ferreira Mendonça, Eliézer Giannini de Barros, Gislaine Ribeiro Pereira, Magali Benjamim de Araújo, Rudy Bonfilio |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Química
2011-01-01
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Series: | Química Nova |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000300027&lng=en&tlng=en |
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