Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia
Objective: To determine the prevalence of patients with CIN1 or less from LEEP specimens in patients with colposcopic biopsy proven CIN2 or 3. Materials and methods: This study was a retrospective–descriptive chart review. Clinical data were retrieved from medical records of women with CIN2 or 3 fro...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-10-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455917301985 |
| _version_ | 1818956924271460352 |
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| author | Sitchuphong Noothong Perapong Inthasorn Malee Warnnissorn |
| author_facet | Sitchuphong Noothong Perapong Inthasorn Malee Warnnissorn |
| author_sort | Sitchuphong Noothong |
| collection | DOAJ |
| description | Objective: To determine the prevalence of patients with CIN1 or less from LEEP specimens in patients with colposcopic biopsy proven CIN2 or 3.
Materials and methods: This study was a retrospective–descriptive chart review. Clinical data were retrieved from medical records of women with CIN2 or 3 from colposcopic biopsy who subsequently underwent LEEP procedure between 2004 and 2014. All pathological slides were reviewed by the gynecologic pathologist. Statistical analyses were performed.
Results: Of 210 patients, 14 patients were excluded from the study. 196 patients were in eligible criteria and data were analyzed. There were 32 patients (16.3%) with CIN1 or less from LEEP specimens who previously had colposcopic biopsies proven CIN2 or 3. Only CIN2 from biopsy was the statistically significant risk factor of CIN1 or less in LEEP specimens. Odds ratio was 10.45 (95% confidence interval: 3.28–33.33, P < 0.001).
Conclusion: The prevalence of patients with CIN1 or less from LEEP specimens who previously had colposcopic biopsies proven CIN2 or 3 was 16.3%. CIN2 from biopsy was the statistically significant risk factor of CIN1 or less in LEEP specimens. |
| first_indexed | 2024-12-20T11:01:41Z |
| format | Article |
| id | doaj.art-0a1b678af4ae4565a6865ccdc9a658ba |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-20T11:01:41Z |
| publishDate | 2017-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-0a1b678af4ae4565a6865ccdc9a658ba2022-12-21T19:43:01ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592017-10-0156562863110.1016/j.tjog.2017.08.009Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasiaSitchuphong Noothong0Perapong Inthasorn1Malee Warnnissorn2Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok 10700, ThailandDepartment of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok 10700, ThailandDepartment of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, ThailandObjective: To determine the prevalence of patients with CIN1 or less from LEEP specimens in patients with colposcopic biopsy proven CIN2 or 3. Materials and methods: This study was a retrospective–descriptive chart review. Clinical data were retrieved from medical records of women with CIN2 or 3 from colposcopic biopsy who subsequently underwent LEEP procedure between 2004 and 2014. All pathological slides were reviewed by the gynecologic pathologist. Statistical analyses were performed. Results: Of 210 patients, 14 patients were excluded from the study. 196 patients were in eligible criteria and data were analyzed. There were 32 patients (16.3%) with CIN1 or less from LEEP specimens who previously had colposcopic biopsies proven CIN2 or 3. Only CIN2 from biopsy was the statistically significant risk factor of CIN1 or less in LEEP specimens. Odds ratio was 10.45 (95% confidence interval: 3.28–33.33, P < 0.001). Conclusion: The prevalence of patients with CIN1 or less from LEEP specimens who previously had colposcopic biopsies proven CIN2 or 3 was 16.3%. CIN2 from biopsy was the statistically significant risk factor of CIN1 or less in LEEP specimens.http://www.sciencedirect.com/science/article/pii/S1028455917301985Cervical intraepithelial neoplasiaLEEPCervical biopsy |
| spellingShingle | Sitchuphong Noothong Perapong Inthasorn Malee Warnnissorn Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia Taiwanese Journal of Obstetrics & Gynecology Cervical intraepithelial neoplasia LEEP Cervical biopsy |
| title | Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia |
| title_full | Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia |
| title_fullStr | Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia |
| title_full_unstemmed | Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia |
| title_short | Pathological discrepancy between colposcopic directed cervical biopsy and Loop Electrosurgical-Excision Procedures (LEEPs) in patients with biopsies proven high grade cervical intraepithelial neoplasia |
| title_sort | pathological discrepancy between colposcopic directed cervical biopsy and loop electrosurgical excision procedures leeps in patients with biopsies proven high grade cervical intraepithelial neoplasia |
| topic | Cervical intraepithelial neoplasia LEEP Cervical biopsy |
| url | http://www.sciencedirect.com/science/article/pii/S1028455917301985 |
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