Muscle atrophy in patients wirh ckd results from fgf23/klotho-mediated supression of insulin/igf-i signaling
Muscle atrophy is a significant consequence of chronic kidney disease (CKD) that increases a patient’s risk of mortality and decrease their quality of life. In CKD patients, the circulation levels of FGF23 are significantly increased, but the exact pathological significance of the increase and relat...
Main Authors: | Shinsuke Kido, Yui Hashimoto, Hiroko Segawa, Sawako Tatsumi, Ken-ichi Miyamoto |
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Format: | Article |
Language: | English |
Published: |
The Korean Society of Nephrology
2012-06-01
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Series: | Kidney Research and Clinical Practice |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211913212004688 |
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