Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting

Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting

Abstract Human umbilical cord mesenchymal stem cells-derived small extracellular vesicles (hucMSC-sEVs) have been demonstrated as a therapeutic agent to prevent and treat cisplatin-induced acute kidney injury (AKI). However, hucMSC-sEVs still face many problems and challenges in the repair and treat...

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Bibliographic Details
Main Authors: Peipei Wu, Yuting Tang, Can Jin, Min Wang, Linli Li, Zhong Liu, Hui Shi, Zixuan Sun, Xiaomei Hou, Wenya Chen, Wenrong Xu, Hui Qian
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Nanobiotechnology
Subjects:
Mesenchymal stem cells
Engineered sEVs
Neutrophil membrane
Antioxidant
Acute kidney injury
Online Access:https://doi.org/10.1186/s12951-022-01574-8

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