Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan
The evaluation indexes of antimicrobial use (AMU) in sub-prefectural regions have not been established because these regional units are susceptible to the effects of population inflows and outflows. We defined the difference in AMU calculated each year as a new evaluation index and compared the AMU...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/11/6/763 |
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| author | Kanako Mizuno Ryo Inose Yuna Matsui Mai Takata Daisuke Yamasaki Yoshiki Kusama Ryuji Koizumi Masahiro Ishikane Masaki Tanabe Hiroki Ohge Norio Ohmagari Yuichi Muraki |
| author_facet | Kanako Mizuno Ryo Inose Yuna Matsui Mai Takata Daisuke Yamasaki Yoshiki Kusama Ryuji Koizumi Masahiro Ishikane Masaki Tanabe Hiroki Ohge Norio Ohmagari Yuichi Muraki |
| author_sort | Kanako Mizuno |
| collection | DOAJ |
| description | The evaluation indexes of antimicrobial use (AMU) in sub-prefectural regions have not been established because these regional units are susceptible to the effects of population inflows and outflows. We defined the difference in AMU calculated each year as a new evaluation index and compared the AMU of secondary medical areas with those already reported for Japan and each prefecture. Patients/1000 inhabitants/day (PID) for oral antibiotics in 2013 and 2016 were calculated using the National Database of Health Insurance Claims and Specific Health Checkups. ΔPID was defined as the difference between the PIDs in 2013 and 2016. Differences in AMUs for Japan and prefectures that have already been published were also calculated, and the concordance rate with ΔPID in each secondary medical area was evaluated. Antibiotics and age groups with less than 50% concordance between secondary medical area and previously reported AMU changes were observed. This revealed that even at the secondary medical area level, which is more detailed than the prefectural level, the AMU changes were not consistent. Therefore, in order to appropriately promote measures against antimicrobial resistance, we suggest the necessity of not only surveying AMU at the national or prefectural levels but also examining sub-prefectural trends in AMU. |
| first_indexed | 2024-03-10T00:36:00Z |
| format | Article |
| id | doaj.art-0a204cdb07ad40b699f8e5b8ef193073 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T00:36:00Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-0a204cdb07ad40b699f8e5b8ef1930732023-11-23T15:16:52ZengMDPI AGAntibiotics2079-63822022-06-0111676310.3390/antibiotics11060763Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of JapanKanako Mizuno0Ryo Inose1Yuna Matsui2Mai Takata3Daisuke Yamasaki4Yoshiki Kusama5Ryuji Koizumi6Masahiro Ishikane7Masaki Tanabe8Hiroki Ohge9Norio Ohmagari10Yuichi Muraki11Department of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, JapanDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, JapanDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, JapanDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, JapanDepartment of Infection Control and Prevention, Mie University Hospital, Tsu 514-8507, JapanDivision of General Pediatrics, Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center, Amagasakic 660-8550, JapanAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo 162-8655, JapanAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo 162-8655, JapanDepartment of Infection Control and Prevention, Mie University Hospital, Tsu 514-8507, JapanDepartment of Infectious Diseases, Hiroshima University Hospital, Hiroshima 734-8551, JapanAMR Clinical Reference Center, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo 162-8655, JapanDepartment of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto 607-8414, JapanThe evaluation indexes of antimicrobial use (AMU) in sub-prefectural regions have not been established because these regional units are susceptible to the effects of population inflows and outflows. We defined the difference in AMU calculated each year as a new evaluation index and compared the AMU of secondary medical areas with those already reported for Japan and each prefecture. Patients/1000 inhabitants/day (PID) for oral antibiotics in 2013 and 2016 were calculated using the National Database of Health Insurance Claims and Specific Health Checkups. ΔPID was defined as the difference between the PIDs in 2013 and 2016. Differences in AMUs for Japan and prefectures that have already been published were also calculated, and the concordance rate with ΔPID in each secondary medical area was evaluated. Antibiotics and age groups with less than 50% concordance between secondary medical area and previously reported AMU changes were observed. This revealed that even at the secondary medical area level, which is more detailed than the prefectural level, the AMU changes were not consistent. Therefore, in order to appropriately promote measures against antimicrobial resistance, we suggest the necessity of not only surveying AMU at the national or prefectural levels but also examining sub-prefectural trends in AMU.https://www.mdpi.com/2079-6382/11/6/763National Database of Health Insurance Claims and Specific Health Checkupsantimicrobial useDDDs/1000 inhabitants per dayDOTs/1000 inhabitants per dayPatients/1000 inhabitants/daysecondary medical area |
| spellingShingle | Kanako Mizuno Ryo Inose Yuna Matsui Mai Takata Daisuke Yamasaki Yoshiki Kusama Ryuji Koizumi Masahiro Ishikane Masaki Tanabe Hiroki Ohge Norio Ohmagari Yuichi Muraki Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan Antibiotics National Database of Health Insurance Claims and Specific Health Checkups antimicrobial use DDDs/1000 inhabitants per day DOTs/1000 inhabitants per day Patients/1000 inhabitants/day secondary medical area |
| title | Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan |
| title_full | Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan |
| title_fullStr | Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan |
| title_full_unstemmed | Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan |
| title_short | Search for Indexes to Evaluate Trends in Antibiotic Use in the Sub-Prefectural Regions Using the National Database of Health Insurance Claims and Specific Health Checkups of Japan |
| title_sort | search for indexes to evaluate trends in antibiotic use in the sub prefectural regions using the national database of health insurance claims and specific health checkups of japan |
| topic | National Database of Health Insurance Claims and Specific Health Checkups antimicrobial use DDDs/1000 inhabitants per day DOTs/1000 inhabitants per day Patients/1000 inhabitants/day secondary medical area |
| url | https://www.mdpi.com/2079-6382/11/6/763 |
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