Mesenchymal stem cells alleviate dexamethasone-induced muscle atrophy in mice and the involvement of ERK1/2 signalling pathway

Mesenchymal stem cells alleviate dexamethasone-induced muscle atrophy in mice and the involvement of ERK1/2 signalling pathway

Abstract Background High dosage of dexamethasone (Dex) is an effective treatment for multiple diseases; however, it is often associated with severe side effects including muscle atrophy, resulting in higher risk of falls and poorer life quality of patients. Cell therapy with mesenchymal stem cells (...

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Bibliographic Details
Main Authors: Belle Yu-Hsuan Wang, Allen Wei-Ting Hsiao, Hoi Ting Shiu, Nicodemus Wong, Amanda Yu-Fan Wang, Chien-Wei Lee, Oscar Kuang-Sheng Lee, Wayne Yuk-Wai Lee
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cell
Muscle atrophy
Dexamethasone
Cell therapy
Online Access:https://doi.org/10.1186/s13287-023-03418-0

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