Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia
Background: Inhalational anaesthetics are used for the induction and maintenance of general anaesthesia in children. More agents are evolving in an effort to discover the agent of choice in this age group, considering the safety margin, availability, affordability, and accessibility of the anaesthet...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Nigerian Journal of Medicine |
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| Online Access: | http://www.njmonline.org/article.asp?issn=1115-2613;year=2023;volume=32;issue=1;spage=23;epage=27;aulast=Yunus |
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| author | Abdulghaffar Adeniyi Yunus M Odigbo S Tasiu S M Babangida Y A Yunusa A M Kabiru M M Yusuf |
| author_facet | Abdulghaffar Adeniyi Yunus M Odigbo S Tasiu S M Babangida Y A Yunusa A M Kabiru M M Yusuf |
| author_sort | Abdulghaffar Adeniyi Yunus |
| collection | DOAJ |
| description | Background: Inhalational anaesthetics are used for the induction and maintenance of general anaesthesia in children. More agents are evolving in an effort to discover the agent of choice in this age group, considering the safety margin, availability, affordability, and accessibility of the anaesthetics. Aim: The aim of our study was to compare the qualities of halothane and sevoflurane in paediatric patients. Materials and Methods: This was a prospective randomised study of 100 children within the age group of 5–12 years, scheduled for elective surgery in Ahmadu Bello University Teaching Hospital, Zaria, from January to October 2022, and satisfied the study inclusion criteria. The following variables (heart rate, blood pressure, arrhythmias, and complications) were recorded and analysed using IBM SPSS version 25 (Chicago) USA. P ≤ 0.05 was considered statistically significant. Results: The incidence of tolerability at induction of anaesthesia, hypoxaemia (SpO2 <90%), and airway responses (laryngospasm, coughing, and breath holding) was similar in both the groups. However, at induction of anaesthesia, the degree of muscle rigidity in the sevoflurane group was statistically significant compared with the halothane group (P = 0.028), but the difference was not statistically significant at the recovery period (P = 0.59). More so, the incidence of arrhythmias was higher in the halothane group than in the sevoflurane group. Conclusion: The overall qualities of halothane were commensurate with that of sevoflurane. However, where available and affordable, sevoflurane will be a better agent of choice in paediatric anaesthesia. |
| first_indexed | 2024-03-12T13:43:43Z |
| format | Article |
| id | doaj.art-0a28d3636f904a68bd72f8e7c133f478 |
| institution | Directory Open Access Journal |
| issn | 1115-2613 |
| language | English |
| last_indexed | 2024-03-12T13:43:43Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Nigerian Journal of Medicine |
| spelling | doaj.art-0a28d3636f904a68bd72f8e7c133f4782023-08-23T09:46:50ZengWolters Kluwer Medknow PublicationsNigerian Journal of Medicine1115-26132023-01-01321232710.4103/NJM.NJM_126_22Comparison of the Qualities of Sevoflurane and Halothane in Paediatric AnaesthesiaAbdulghaffar Adeniyi YunusM OdigboS TasiuS M BabangidaY A YunusaA M KabiruM M YusufBackground: Inhalational anaesthetics are used for the induction and maintenance of general anaesthesia in children. More agents are evolving in an effort to discover the agent of choice in this age group, considering the safety margin, availability, affordability, and accessibility of the anaesthetics. Aim: The aim of our study was to compare the qualities of halothane and sevoflurane in paediatric patients. Materials and Methods: This was a prospective randomised study of 100 children within the age group of 5–12 years, scheduled for elective surgery in Ahmadu Bello University Teaching Hospital, Zaria, from January to October 2022, and satisfied the study inclusion criteria. The following variables (heart rate, blood pressure, arrhythmias, and complications) were recorded and analysed using IBM SPSS version 25 (Chicago) USA. P ≤ 0.05 was considered statistically significant. Results: The incidence of tolerability at induction of anaesthesia, hypoxaemia (SpO2 <90%), and airway responses (laryngospasm, coughing, and breath holding) was similar in both the groups. However, at induction of anaesthesia, the degree of muscle rigidity in the sevoflurane group was statistically significant compared with the halothane group (P = 0.028), but the difference was not statistically significant at the recovery period (P = 0.59). More so, the incidence of arrhythmias was higher in the halothane group than in the sevoflurane group. Conclusion: The overall qualities of halothane were commensurate with that of sevoflurane. However, where available and affordable, sevoflurane will be a better agent of choice in paediatric anaesthesia.http://www.njmonline.org/article.asp?issn=1115-2613;year=2023;volume=32;issue=1;spage=23;epage=27;aulast=Yunushalothanepaediatric patientsquality of anaesthesiasevoflurane |
| spellingShingle | Abdulghaffar Adeniyi Yunus M Odigbo S Tasiu S M Babangida Y A Yunusa A M Kabiru M M Yusuf Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia Nigerian Journal of Medicine halothane paediatric patients quality of anaesthesia sevoflurane |
| title | Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia |
| title_full | Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia |
| title_fullStr | Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia |
| title_full_unstemmed | Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia |
| title_short | Comparison of the Qualities of Sevoflurane and Halothane in Paediatric Anaesthesia |
| title_sort | comparison of the qualities of sevoflurane and halothane in paediatric anaesthesia |
| topic | halothane paediatric patients quality of anaesthesia sevoflurane |
| url | http://www.njmonline.org/article.asp?issn=1115-2613;year=2023;volume=32;issue=1;spage=23;epage=27;aulast=Yunus |
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