Probiotic Escherichia coli Nissle 1917 Expressing Elafin Protects Against Inflammation and Restores the Gut Microbiota

Probiotic Escherichia coli Nissle 1917 Expressing Elafin Protects Against Inflammation and Restores the Gut Microbiota

Intestinal mucosal inflammation and epithelial barrier dysfunction have been implicated as pathological factors in inflammatory bowel disease (IBD). An emerging area of IBD research focuses on probiotics. The probiotic Escherichia coli Nissle 1917 (EcN) is an excellent choice for engineering therape...

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Bibliographic Details
Main Authors: Guigen Teng, Zilin Liu, Yun Liu, Ting Wu, Yun Dai, Huahong Wang, Weihong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Microbiology
Subjects:
Elafin
EcN
gut microbiota
inflammatory bowel disease
intestinal epithelial barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.819336/full

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