Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidism
Objective: To find changes in voice quality, airway invasion during swallowing, pharyngeal residue after swallowing, acoustic and aerodynamic measurements and pulmonary function tests after total parathyroidectomy plus auto-transplantation for secondary hyperparathyroidism. Methods: We recruited 38...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | Asian Journal of Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1015958421008289 |
| _version_ | 1811180708937334784 |
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| author | Fong-Fu Chou Jin-Bor Chen Shun-Chen Huang Yi-Chia Chan Shun-Yu Chi Chi-Chih Lai Yi-Ju Wu Huang-Chih Chang |
| author_facet | Fong-Fu Chou Jin-Bor Chen Shun-Chen Huang Yi-Chia Chan Shun-Yu Chi Chi-Chih Lai Yi-Ju Wu Huang-Chih Chang |
| author_sort | Fong-Fu Chou |
| collection | DOAJ |
| description | Objective: To find changes in voice quality, airway invasion during swallowing, pharyngeal residue after swallowing, acoustic and aerodynamic measurements and pulmonary function tests after total parathyroidectomy plus auto-transplantation for secondary hyperparathyroidism. Methods: We recruited 38 patients who underwent successful surgery for secondary hyperparathyroidism in this study. Voice quality was evaluated using voice handicap index (VHI-10), eating assessment tool (EAT-10), voice impairment, and the grade, roughness, breathiness, asthenia, strain (GRBAS) scale. Acoustic and aerodynamic measurements included fundamental frequency (F0), maximal phonation time, high pitch, jitter, s/z, shimmer and noise-to-harmonic ratio. Vocal cord mobility, vocal cord closure, premature spillage, the penetration–aspiration scale and the Yale pharyngeal residue severity rating scale (PRSRS) after swallowing were examined using fiber-optic endoscopy. Pulmonary function tests included forced vital capacity, forced expiratory volume in 1 s, bronchodilator test, total lung capacity, diffusion capacity of the lung for carbon monoxide, alveolar volume, and distance and O2 desaturation of the 6 min walking test (6MWT). Results: Four months after successful parathyroidectomy, VHI-10 improved significantly (p < 0.01); incomplete vocal cord closure decreased significantly (p < 0.01); the Yale PRSRS for vallecula and pyriform sinus improved significantly (p = 0.02 and p = 0.02); F0 and high pitch increased significantly (p < 0.01 and p = 0.01); O2 desaturation (<4%) of 6MWT improved significantly (p = 0.04). Conclusions: Parathyroidectomy for secondary hyperparathyroidism can improve the voice quality, vocal cord closure, the Yale PRSRS for vallecular and pyriform sinus and O2 desaturation of 6MWT, and increase F0 and high pitch. |
| first_indexed | 2024-04-11T09:07:53Z |
| format | Article |
| id | doaj.art-0a2d032182bd48cf89a6406546cf4ff5 |
| institution | Directory Open Access Journal |
| issn | 1015-9584 |
| language | English |
| last_indexed | 2024-04-11T09:07:53Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Surgery |
| spelling | doaj.art-0a2d032182bd48cf89a6406546cf4ff52022-12-22T04:32:35ZengElsevierAsian Journal of Surgery1015-95842022-11-01451122732279Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidismFong-Fu Chou0Jin-Bor Chen1Shun-Chen Huang2Yi-Chia Chan3Shun-Yu Chi4Chi-Chih Lai5Yi-Ju Wu6Huang-Chih Chang7Division of General Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Corresponding author. 123 Ta-Pei Rd. Niao-Sung District, Kaohsiung, Taiwan.Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, TaiwanDepartment of Pathology, Kaohsiung Chang Gung Memorial Hospital, TaiwanDivision of General Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, TaiwanDivision of General Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, TaiwanDepartment of Otolaryngology (ENT), Kaohsiung Chang Gung Memorial Hospital, TaiwanDivision of General Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, TaiwanDivision of Chest Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, TaiwanObjective: To find changes in voice quality, airway invasion during swallowing, pharyngeal residue after swallowing, acoustic and aerodynamic measurements and pulmonary function tests after total parathyroidectomy plus auto-transplantation for secondary hyperparathyroidism. Methods: We recruited 38 patients who underwent successful surgery for secondary hyperparathyroidism in this study. Voice quality was evaluated using voice handicap index (VHI-10), eating assessment tool (EAT-10), voice impairment, and the grade, roughness, breathiness, asthenia, strain (GRBAS) scale. Acoustic and aerodynamic measurements included fundamental frequency (F0), maximal phonation time, high pitch, jitter, s/z, shimmer and noise-to-harmonic ratio. Vocal cord mobility, vocal cord closure, premature spillage, the penetration–aspiration scale and the Yale pharyngeal residue severity rating scale (PRSRS) after swallowing were examined using fiber-optic endoscopy. Pulmonary function tests included forced vital capacity, forced expiratory volume in 1 s, bronchodilator test, total lung capacity, diffusion capacity of the lung for carbon monoxide, alveolar volume, and distance and O2 desaturation of the 6 min walking test (6MWT). Results: Four months after successful parathyroidectomy, VHI-10 improved significantly (p < 0.01); incomplete vocal cord closure decreased significantly (p < 0.01); the Yale PRSRS for vallecula and pyriform sinus improved significantly (p = 0.02 and p = 0.02); F0 and high pitch increased significantly (p < 0.01 and p = 0.01); O2 desaturation (<4%) of 6MWT improved significantly (p = 0.04). Conclusions: Parathyroidectomy for secondary hyperparathyroidism can improve the voice quality, vocal cord closure, the Yale PRSRS for vallecular and pyriform sinus and O2 desaturation of 6MWT, and increase F0 and high pitch.http://www.sciencedirect.com/science/article/pii/S1015958421008289O2 desaturationParathyroidectomySecondary hyperparathyroidismSwallowVoice quality |
| spellingShingle | Fong-Fu Chou Jin-Bor Chen Shun-Chen Huang Yi-Chia Chan Shun-Yu Chi Chi-Chih Lai Yi-Ju Wu Huang-Chih Chang Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidism Asian Journal of Surgery O2 desaturation Parathyroidectomy Secondary hyperparathyroidism Swallow Voice quality |
| title | Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidism |
| title_full | Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidism |
| title_fullStr | Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidism |
| title_full_unstemmed | Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidism |
| title_short | Changes in voice quality, swallowing, and pulmonary function after parathyroidectomy for secondary hyperparathyroidism |
| title_sort | changes in voice quality swallowing and pulmonary function after parathyroidectomy for secondary hyperparathyroidism |
| topic | O2 desaturation Parathyroidectomy Secondary hyperparathyroidism Swallow Voice quality |
| url | http://www.sciencedirect.com/science/article/pii/S1015958421008289 |
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