Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature Representation

Ground-glass nodules (GGN) are the main manifestation of early lung cancer, and accurate and efficient identification of ground-glass pulmonary nodules is of great significance for the treatment of lung diseases. In response to the problem of traditional machine learning requiring manual feature ext...

Full description

Bibliographic Details
Main Authors: Jun Miao, Maoxuan Zhang, Yiru Chang, Yuanhua Qiao
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Symmetry
Subjects:
Online Access:https://www.mdpi.com/2073-8994/15/12/2192
_version_ 1797379266221965312
author Jun Miao
Maoxuan Zhang
Yiru Chang
Yuanhua Qiao
author_facet Jun Miao
Maoxuan Zhang
Yiru Chang
Yuanhua Qiao
author_sort Jun Miao
collection DOAJ
description Ground-glass nodules (GGN) are the main manifestation of early lung cancer, and accurate and efficient identification of ground-glass pulmonary nodules is of great significance for the treatment of lung diseases. In response to the problem of traditional machine learning requiring manual feature extraction, and most deep learning models applied to 2D image classification, this paper proposes a Transformer-based recognition model for ground-glass nodules from the view of global 3D asymmetry feature representation. Firstly, a 3D convolutional neural network is used as the backbone to extract the features of the three-dimensional CT-image block of pulmonary nodules automatically; secondly, positional encoding information is added to the extracted feature map and input into the Transformer encoder layer for further extraction of global 3D asymmetry features, which can preserve more spatial information and obtain higher-order asymmetry feature representation; finally, the extracted asymmetry features are entered into a support vector machine or ELM-KNN model to further improve the recognition ability of the model. The experimental results show that the recognition accuracy of the proposed method reaches 95.89%, which is 4.79, 2.05, 4.11, and 2.74 percentage points higher than the common deep learning models of AlexNet, DenseNet121, GoogLeNet, and VGG19, respectively; compared with the latest models proposed in the field of pulmonary nodule classification, the accuracy has been improved by 2.05, 2.05, and 0.68 percentage points, respectively, which can effectively improve the recognition accuracy of ground-glass nodules.
first_indexed 2024-03-08T20:19:41Z
format Article
id doaj.art-0a30ed8cfafa4f48aba995d1c8128913
institution Directory Open Access Journal
issn 2073-8994
language English
last_indexed 2024-03-08T20:19:41Z
publishDate 2023-12-01
publisher MDPI AG
record_format Article
series Symmetry
spelling doaj.art-0a30ed8cfafa4f48aba995d1c81289132023-12-22T14:45:22ZengMDPI AGSymmetry2073-89942023-12-011512219210.3390/sym15122192Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature RepresentationJun Miao0Maoxuan Zhang1Yiru Chang2Yuanhua Qiao3School of Computer Science, Beijing Information Science and Technology University, Beijing 100101, ChinaSchool of Computer Science, Beijing Information Science and Technology University, Beijing 100101, ChinaSchool of Computer Science, Beijing Information Science and Technology University, Beijing 100101, ChinaCollege of Applied Sciences, Beijing University of Technology, Beijing 100124, ChinaGround-glass nodules (GGN) are the main manifestation of early lung cancer, and accurate and efficient identification of ground-glass pulmonary nodules is of great significance for the treatment of lung diseases. In response to the problem of traditional machine learning requiring manual feature extraction, and most deep learning models applied to 2D image classification, this paper proposes a Transformer-based recognition model for ground-glass nodules from the view of global 3D asymmetry feature representation. Firstly, a 3D convolutional neural network is used as the backbone to extract the features of the three-dimensional CT-image block of pulmonary nodules automatically; secondly, positional encoding information is added to the extracted feature map and input into the Transformer encoder layer for further extraction of global 3D asymmetry features, which can preserve more spatial information and obtain higher-order asymmetry feature representation; finally, the extracted asymmetry features are entered into a support vector machine or ELM-KNN model to further improve the recognition ability of the model. The experimental results show that the recognition accuracy of the proposed method reaches 95.89%, which is 4.79, 2.05, 4.11, and 2.74 percentage points higher than the common deep learning models of AlexNet, DenseNet121, GoogLeNet, and VGG19, respectively; compared with the latest models proposed in the field of pulmonary nodule classification, the accuracy has been improved by 2.05, 2.05, and 0.68 percentage points, respectively, which can effectively improve the recognition accuracy of ground-glass nodules.https://www.mdpi.com/2073-8994/15/12/2192ground-glass nodules3D ResNettransformersupport vector machineELM-KNN
spellingShingle Jun Miao
Maoxuan Zhang
Yiru Chang
Yuanhua Qiao
Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature Representation
Symmetry
ground-glass nodules
3D ResNet
transformer
support vector machine
ELM-KNN
title Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature Representation
title_full Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature Representation
title_fullStr Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature Representation
title_full_unstemmed Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature Representation
title_short Transformer-Based Recognition Model for Ground-Glass Nodules from the View of Global 3D Asymmetry Feature Representation
title_sort transformer based recognition model for ground glass nodules from the view of global 3d asymmetry feature representation
topic ground-glass nodules
3D ResNet
transformer
support vector machine
ELM-KNN
url https://www.mdpi.com/2073-8994/15/12/2192
work_keys_str_mv AT junmiao transformerbasedrecognitionmodelforgroundglassnodulesfromtheviewofglobal3dasymmetryfeaturerepresentation
AT maoxuanzhang transformerbasedrecognitionmodelforgroundglassnodulesfromtheviewofglobal3dasymmetryfeaturerepresentation
AT yiruchang transformerbasedrecognitionmodelforgroundglassnodulesfromtheviewofglobal3dasymmetryfeaturerepresentation
AT yuanhuaqiao transformerbasedrecognitionmodelforgroundglassnodulesfromtheviewofglobal3dasymmetryfeaturerepresentation