Deciphering Promoter Hypermethylation of Genes Encoding for RASSF/Hippo Pathway Reveals the Poor Prognostic Factor of RASSF2 Gene Silencing in Colon Cancers

Deciphering Promoter Hypermethylation of Genes Encoding for RASSF/Hippo Pathway Reveals the Poor Prognostic Factor of RASSF2 Gene Silencing in Colon Cancers

The aims of this study were to assess the frequency of promoter hypermethylation of the genes encoding the Ras associated domain family (RASSF)/Hippo pathway, as well as the impact on overall (OS) and progression-free survival (PFS) in a single-center retrospective cohort of 229 patients operated on...

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Bibliographic Details
Main Authors: Marc Riffet, Yassine Eid, Maxime Faisant, Audrey Fohlen, Benjamin Menahem, Arnaud Alves, Fatéméh Dubois, Guénaelle Levallet, Céline Bazille
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
colon cancers
RASSF/Hippo pathway
molecular biomarker
Online Access:https://www.mdpi.com/2072-6694/13/23/5957

Internet

https://www.mdpi.com/2072-6694/13/23/5957

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